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SUMMARY:Regulation of Translation in Relation to Cell Fate
DTSTART:20180907T110000
DTEND:20180907T120000
DTSTAMP:20260916T225837Z
UID:a31321e2e16a62517c2992509dc67abc1ca6c2c5b2c5e00c5e84883d
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Mihaela Zavolan\, Biozentrum\, University of Basel (CH)\
 nBIOENGINEERING SEMINAR\n\nAbstract:\nCell type specification has been pri
 marily attributed to epigenetic and transcriptional regulation. However\, 
 translation regulation is prominent in early development and several recen
 t studies have linked alterations in protein synthesis to changes in cell 
 functionality. Furthermore\, evidence is accumulating that ribosome varian
 ts contribute to cell type-specific programs of gene expression. In this t
 alk I would like to present our efforts in characterizing the regulation o
 f mRNA translation in relation to cellular states\, from yeast to man. I w
 ill describe our work on inferring determinants of protein synthesis rates
  in yeast\, as well as the relationship between protein synthesis capacity
  and lifespan. I will also discuss aspects of translation regulation in ma
 mmalian system\, specifically relative to cell type and the proliferation 
 rate of cells.\n\nBio:\nPositions:\nSince 2014        Professor in
  Computational Biology/Genomics\, Biozentrum\, University of Basel\n2008 
 – 2014      Associate Professor in Computational and Systems Biolog
 y\, Biozentrum\, University of Basel\n2003 – 2008      Assistant Pr
 ofessor in Computational and Systems Biology\, Biozentrum\, University of 
 Basel\nSince 2003       Group leader at the SIB Swiss Institute of B
 ioinformatics\n2000 – 2003      Postdoctoral Fellow in the Laborato
 ry of Computational Biology\, The Rockefeller University\, NY\, USA.\n1999
  – 2000      Postdoctoral fellow in the division of theoretical bio
 logy and biophysics\, Los Alamos National Laboratory\, NM\, USA\n1996 – 
 1999      Teaching assistant and lecturer for the introductory progra
 mming class at Computer Science Department\, University of New Mexico\, Al
 buquerque\, NM\, USA\n1994 – 1996      Research associate at the di
 vision of Theoretical Biology and Biophysics\, Los Alamos National Laborat
 ory\, Los Alamos\, NM\, USA\n1993 – 1994      Research associate\, 
 Theoretical Immunology Program\, The Santa Fe Institute\, Santa Fe\, NM\, 
 USA\n            \nEducation:\nSince 1999        Ph.D. in 
 Computer Science\, University of New Mexico\, Albuquerque\, NM\, USA in th
 e group of Dr. Stephanie Forrest.\nSince 1996        M. Sc. in Com
 puter Science\, University of New Mexico\, Albuquerque\, NM\, USA\nSince 1
 992        MD at the Univeristy of Medicine and Pharmacy of Timiso
 ara\, Romania.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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