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SUMMARY:Single-Particle Tracking of Small Nanoparticles in Nanocapillaries
DTSTART:20180903T151500
DTEND:20180903T161500
DTSTAMP:20260919T231425Z
UID:f64afaa070b87e8d172bf94fece8303a71557f1cc666198e47a50810
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Sanli Faez\, Debye Institute for Nanomaterials Research\
 , Utrecht University\, Utrecht (NL)\nBIOENGINEERING SEMINAR\n\nAbstract:\n
 I introduce nanoCapillary Electrokinetic Tracking (nanoCET)\, an optofluid
 ic platform for continuously measuring the electrophoretic mobility of a s
 ingle colloidal nanoparticles or macromolecule in vitro with millisecond t
 ime resolution and high charge sensitivity. This platform uses a nanobore 
 optical fiber in which liquids flow inside the light-guiding core and nano
 particles are tracked using elastic light scattering. Our group has achiev
 ed experimental tracking of nanoparticles down to 10 nm in size inside an 
 aqueous environment. I will explain the necessary steps for extending this
  method to probing single biomolecules.\n \nTo further extend the sensing
  capability of nanoCET to dense biological samples\, transport of particle
 s into and through the nanobore fiber should be controlled over long measu
 rement periods. At this sizes pumping is only possible by electroosmosis\,
  but also involve major challenges. I will discuss the mechanism of jammin
 g at the channel entry and how to avoid it\, which is an important step fo
 r using nanobore fibers and other nanopore structures.\n \nRealizing such
  a flow control in the nanoCET platform will immensely facilitate the daun
 ting challenge of monitoring biochemical or catalytic reactions on a singl
 e entity over a wide range of timescales. The unique measurement capabilit
 ies of this platform are relevant for a wide range of applications  in co
 lloid science\, analytical biochemistry\, and medical diagnostics.\n\nBio:
 \n(from https://sanlifaez.github.io/about/)\nI am an assistant professor a
 t the Physics department of Utrecht University. I am also a member of Utre
 cht Young Academy and taskforce open-science.\nI studied Physics at the Sh
 arif University of Technology and recieved my master’s degree in Nanotec
 hnology from University of Twente. My master and PhD projects were both on
  wave propagation in random media and Anderson localization\, at the (form
 er) FOM institute AMOLF\, under the supervision of Ad Lagendijk. I recieve
 d my doctorate degree in 2011 from the Univesity of Amsterdam. I joined th
 e Sandoghdar division at the Max Planck Institute for the Science of Light
  as a post-doc\, where I devised a new scheme for coherent coupling betwee
 n single organic molecules and dielectric waveguides. In August 2013\, I m
 oved to the Single-Molecule Optics group\, led by Michel Orrit\, at the Le
 iden institute of Physics and started working on tracing single electrons 
 using single molecule spectroscopy. During my stay at Leiden\, I also deve
 loped the nanocapillary electrophoretic tracking (nanoCET) technique with 
 the goal of studying rapid changes in the electrophoretic mobility of sing
 le mobile nanoparticles.\nIn August 2015\, together with Allard Mosk\, we 
 started a new research group named Physics of Light in Complex Systems\,na
 noLINX. In this group\, I am the principle investigator for the research d
 irection nanoElectroPhotonics.\nMy hobbies are rowing\, listening to and m
 aking podcasts\, and making Physics-related table-top demonstrations.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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