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SUMMARY:Tissue-engineering for implantable bionics
DTSTART:20180907T113000
DTEND:20180907T123000
DTSTAMP:20260407T002727Z
UID:b9b189c3f68610f6c73bc5fb568528e50d850fc3237de46827ef8a31
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr Rylie Green\, Senior Lecturer\, Department of Bioengineeri
 ng\, Imperial College London\nAbstract\nOver the past 30 years implantable
  bionic devices such as cochlear implants and pacemakers\, have used a sma
 ll number of metal electrodes to restore sensory perception or muscle cont
 rol to patients following disease or injury of excitable tissues. With the
  miniaturisation of electronic chips\, bionic devices are now being develo
 ped to treat a wide variety of neural and muscular disorders. Of particula
 r interest is the area of high resolution devices that require smaller\, m
 ore densely packed electrodes. Due to poor integration with living tissue\
 , conventional metallic electrodes cannot meet these small size requiremen
 ts and are limited in their ability to safely deliver charge at therapeuti
 c levels. A range of alternate electrode coating materials have been inves
 tigated by Dr Green including conductive hydrogels (CHs)\, conductive elas
 tomers (CEs) and living electrodes (LEs) which provide synergy between low
  impedance charge transfer\, reduced stiffness and an ability to be provid
 e a biologically active interface. While these approaches have initially b
 een used to modify existing implant electrodes (including cochlear implant
 s and bionics eye arrays)\, these technologies also offer new opportunitie
 s for producing fully organic electrode arrays which are not bound to meta
 llic substrates. This talk will outline materials development and characte
 risation of both in vitro properties and translational in vivo performance
 . The challenges for translation and commercial uptake of novel technologi
 es will also be discussed.\n \nBiography:\nDr Rylie Green joined the Bioe
 ngineering department at Imperial College London in 2016. She received her
  PhD (Biomedical Engineering) from the University of New South Wales\, Aus
 tralia in 2008. Dr Green’s research has been broadly focused on developi
 ng medical electrodes\, with a specific focus on neuroprostheses. Her rese
 arch is split into two related streams (i) biomaterials and tissue enginee
 ring\; and (ii) bionics and device design. While Dr Green’s research has
  been focused on developing bioactive conducting polymers to improve perfo
 rmance of stimulating electrodes\, she has also developed a range of techn
 iques for characterising the in vitro performance of implantable microelec
 trodes in biologically relevant environments. Specifically\, she has inves
 tigated electrode technologies for the developmental bionic eye device (wi
 th Bionic Vision Australia)\, and coatings for commercial implants (with C
 ochlear Ltd\, Galvani Bioelectronics and Boston Scientific). More recently
  Dr Green has developed hybrids of conducting polymers and hydrogels to re
 duce strain mismatch with neural tissue and improve long-term cell interac
 tions at the neural interface. This has led to her development of tissue e
 ngineered “living electrodes”\, a new concept which will allow neural 
 cells to synaptically interface with bionic devices.
LOCATION:CM 1 120 https://plan.epfl.ch/?room==CM%201%20120
STATUS:CONFIRMED
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