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BEGIN:VEVENT
SUMMARY:Environmental signals tune bacterial growth and physiology
DTSTART:20181116T131500
DTEND:20181116T141500
DTSTAMP:20260922T182530Z
UID:47fe9bf2247e0fbda0b66bc620b4b2bec244192723b6a67a92f896c7
CATEGORIES:Conferences - Seminars
DESCRIPTION:Professor Petra Anne Levin\, professor in the Department of Bi
 ology in Washington University in St. Louis\, MO\, USA. Co-Director Plant 
 and Microbial Biosciences Graduate Program\nBacterial morphology is a comp
 lex trait\, influenced by genetic and environmental factors alike.  To da
 te\, analysis of environmental determinants of bacterial shape has been re
 stricted to nutrient-derived signals. Comparatively little is known about 
 the contribution of chemical and physical cues to cell size homeostasis. I
 n this talk\, I will present data supporting extracellular pH as an enviro
 nmental signal capable of modulating cell wall synthesis and cell size in 
 the rod-shaped bacterium Escherichia coli. Modest reductions in pH alter t
 he activity of the division machinery resulting in changes in cell length.
  Changes in pH also enhance recruitment and activation of periplasmic cell
  wall synthesis enzymes\, rendering cells resistant to specific classes of
  antibiotics. Together these data reveal cell wall metabolism in E. coli t
 o be highly responsive to chemical cues\, bolstering fitness across enviro
 nmental conditions. \n 
LOCATION:BSP 231 https://plan.epfl.ch/?dim_floor=2&lang=fr&dim_lang=fr&tre
 e_groups=centres_nevralgiques%2Cacces%2Cmobilite_reduite%2Censeignement%2C
 commerces_et_services%2Cvehicules%2Cinfrastructure_plan_grp&tree_grou
STATUS:CONFIRMED
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