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SUMMARY:Micro/Nano/Biotechnology Device Integration for Addressing Gastroi
 ntestinal Health
DTSTART:20190211T101500
DTEND:20190211T113000
DTSTAMP:20260502T061207Z
UID:99abcaf6efb1389e32d79fd122176ef55f4cc112c8c15c9af417ebcc
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Dr. Reza Ghodssi\nUniversity of Maryland \nInstitute of 
 Microengineering - Distinguished Lecture\n\nCampus Lausanne SV 1717 (live)
 \nCampus Microcity MC B0 302 (video)\nZoom Live Stream: https://epfl.zoom.
 us/j/108318318\n\nAbstract: The development of integrated systems for inve
 stigating gut health continues to be a major focus of biomedical research.
  While our understanding of gastrointestinal (GI) health has advanced more
  than ever\, a lack of comprehensive tools hinders our ability to explore 
 gaps in knowledge to improve evaluation and management strategies. Through
  ongoing innovations in micro- and nano-electronics\, next-generation inte
 grated devices are emerging to sample and sense GI fluids by providing rea
 l-time monitoring of biochemical and bacterial behavior and its impact on 
 GI cancer development and gut-brain signaling. Our group focuses on develo
 ping and integrating new technologies into ingestible capsule systems for 
 in vivo navigation and biochemical sensing of GI contents. This includes h
 ybrid packaging strategies for sampling select GI regions through integrat
 ing microelectronics modules for wireless transmission of sensor signals t
 o mobile receivers. To understand sensing and analysis in in vivo environm
 ents\, we are developing in vitro models to monitor cellular behaviors und
 erlying both the gut-microbiome-brain-axis (GMBA) and bacterial biofilm fo
 rmation. Our GMBA model consists of an in vitro cell-sensor-interfaced 3D-
 printed platform\, tailored to monitor gut epithelial cell growth and sero
 tonin secretion\, providing information about in vivo interactions between
  bacteria and gut cells. Bacterial biofilms\, a major cause of infection b
 oth in the gut and on virtually all hydrated surfaces\, may be grown and m
 onitored in our flexible platform for real-time in situ sensing and treatm
 ent in a wide range of vulnerable regions. Due to the need for our sensors
  to exhibit selective\, sensitive\, and clinically viable functions\, we a
 re exploring bio-functionalization of sensor electrodes with virus-based m
 acromolecules\, specifically Tobacco Mosaic Virus\, to enhance device perf
 ormance required to detect relevant biomarkers in poorly accessible GI tis
 sues and regions.\n\nBio: Reza Ghodssi is the Herbert Rabin Distinguished 
 Chair in Engineering and Director of the MEMS Sensors and Actuators Lab (M
 SAL) in the Department of Electrical and Computer Engineering (ECE) and th
 e Institute for Systems Research (ISR) at the University of Maryland (UMD)
 . Dr. Ghodssi's research interests are in the design and development of mi
 cro/nano/bio devices and systems for chemical and biological sensing\, sma
 ll-scale energy conversion and harvesting with a strong emphasis toward he
 althcare applications. Dr. Ghodssi was director of the Institute for Syste
 ms Research (ISR) for eight years (2009-2017). During this time\, he launc
 hed a number of interdisciplinary initiatives such as the Maryland Robotic
 s Center (MRC) and the Brain and Behavior Initiative (BBI)\, aimed at enha
 ncing the impact of ISR research efforts on society while building a more 
 interactive faculty\, staff and student community across different discipl
 ines in the institute. Dr. Ghodssi is a University of Maryland Distinguish
 ed Scholar-Teacher\, a Fellow of IEEE\, AVS\, and ASME\, has over 150 jour
 nal publications and 325 refereed conference papers\, and is the co-editor
  of the MEMS Materials and Processes Handbook published in 2011. He is an 
 associate editor for the Journal of Microelectromechanical Systems (JMEMS)
  and Biomedical Microdevices (BMMD). He has obtained eight U.S. patents\, 
 with another seven pending. \n\nNote: The Seminar Series is eligible for 
 ECTS credits in the EDMI doctoral program. 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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