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BEGIN:VEVENT
SUMMARY:Using DNA Origami to Decipher Spatial Effects in Biology
DTSTART:20190304T121500
DTSTAMP:20260406T214534Z
UID:23425f68a4c0dee1972f161c873525ef4af18dcbf83b46c19fec903d
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Björn Högberg\, Karolinska Institute\, Stockholm (SE)\
 nWEEKLY BIOENGINEERING COLLOQUIA SERIES\n(sandwiches served)\n\nAbstract: 
 \nIt is widely accepted that the biophysical context of ligands and recept
 ors has significant impact of downstream signaling\, however the concept i
 s poorly understood due to difficulties in controlling and analyzing the m
 icroenvironment on the nanoscale. I will talk about how we think that DNA-
 nanotechnology can be of great help in both learning the tactile alphabet 
 of cells by stimulation using protein decorated DNA-origami ‘nano-calipe
 rs’ and of help in understanding the binding of antibodies. I will also 
 briefly present our recent work on ‘3D-printing’ DNA origami wireframe
  structures\, a method that provides a way to make origami more accessible
  to experiments in physiological salt conditions.\n\nBio:\nBjörn Högberg
  is a professor of molecular systems biophysics and head of the Division o
 f Biomaterials at the Department of Medical Biochemistry and Biophysics at
  Karolinska Institutet. He is a Knut and Alice Wallenberg Foundation Acade
 my Fellow and an ERC Consolidator grantee.\nHögberg’s research is focus
 ed on developing new methods and molecular tools for cell biology research
  using DNA devices\, mainly DNA nanotechnology and DNA origami. His focus 
 has been both in development of the basic technology and in applications t
 o probe and manipulate cell signaling by cell surface receptor clustering.
  His research also involve using these devices for drug delivery in cancer
 .\nHögberg earned his MSc in Physics at Uppsala University and did his Ph
 D in Physics both at Chalmers University\, where he started\, and at Mid S
 weden University where he graduated in 2007. After that he joined the lab 
 of William Shih as a post-doc at Harvard Medical School and Dana Farber Ca
 ncer Institute in Boston\, USA. He joined Karolinska Institutet in 2010 as
  an Assistant Professor at the dept. of Neuroscience and now holds a facul
 ty positon at the dept. of Medical Biochemistry and Biophysics.\n \n‘Zo
 om’ link for attending remotely: https://epfl.zoom.us/j/331009416\n\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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