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SUMMARY:BMI SEMINAR // Klaas Stephan - Translational Neuromodeling\, Compu
 tational Psychiatry and Computational Psychosomatics
DTSTART:20190213T121500
DTEND:20190213T131500
DTSTAMP:20260405T200437Z
UID:8a20169982cbc63d20816d72e836f6690436dd898668203380b46c59
CATEGORIES:Conferences - Seminars
DESCRIPTION:Klaas Stephan\, Translational Neuromodeling Unit (TNU)\, Insti
 tute for Biomedical Engineering\, University of Zurich & ETH Zurich\, Swit
 zerland\n\nFor many brain diseases\, particularly in psychiatry\, we lack 
 clinical tests for differential diagnosis and cannot predict optimal treat
 ment for individual patients. This presentation outlines a translational n
 euromodeling framework for inferring subject-specific mechanisms of brain 
 disease from non-invasive measures of behaviour and neuronal activity. Gui
 ded by clinical theories of maladaptive cognition and aberrant brain-body 
 interactions\, generative models can be developed that have potential as 
 “computational assays”. Evaluating the clinical utility of these assay
 s requires prospective patient studies that address concrete clinical prob
 lems\, such as treatment response prediction. If successful\, computationa
 l assays may help provide a formal basis for differential diagnosis and tr
 eatment predictions in individual patients and\, ultimately\, facilitate t
 he construction of mechanistically interpretable disease classifications.\
 n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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