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SUMMARY:Subcellular-resolution electrophysiology with CMOS-based high-dens
 ity microelectrode arrays
DTSTART:20190215T110000
DTEND:20190215T120000
DTSTAMP:20260408T072811Z
UID:d6492423f8a8ef7a64f4fcc23be972376af550e9d92880d0c63253ce
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Andreas Hierlemann\, Department Biosystems Science and 
 Engineering\, ETH Zurich\nExtracellular electrical recordings by means of 
 microelectrode arrays complement well-established patch clamp techniques a
 nd optical or optogenetic techniques. The use of CMOS technology helps to
  overcome the connectivity problem of how to interface thousands of tightl
 y-spaced electrodes\, while\, at the same time\, it improves signal-to-noi
 se characteristics\, as signal conditioning is done on chip next to where 
 the partially very small signals (< 10 µV) are generated.  Several diff
 erent approaches relying on open-gate field-effect transistors or metal el
 ectrodes have been pursued.  There are high-density pixel-based approach
 es and realizations based on a switch matrix concept.  State of the art 
 systems enable to\, e.g.\, resolve individual action potentials propagatin
 g along axons. Applications include research in neural diseases and pharma
 cology.\n\n\nAndreas Hierlemann completed his college education in chemis
 try at the University of Tübingen\, Germany\, and was awarded a Ph.D. deg
 ree in 1996. He then held Postdoctoral positions at Texas A & M University
 \, College Station\, TX\, USA\, in 1997\, and at Sandia National Laborator
 ies\, Albuquerque\, NM\, USA\, in 1998. In 1999\, he joined the Department
  of Physics\, ETH Zurich\, Switzerland\, where he was appointed Associate 
 Professor in June 2004. In April 2008\, he became a Full Professor in the 
 Department of Biosystems Science and Engineering (BSSE)\, ETH Zurich\, Bas
 el. His research interests include the development and application of mic
 rosensor\, microfluidic\, and microelectronic technologies to address ques
 tions in biology and medicine with applications in the fields of systems b
 iology\, drug testing\, personalized medicine\, and neuroscience. For deta
 ils\, see https://www.bsse.ethz.ch/bel/.
LOCATION:Campus Biotech H8-01-D
STATUS:CONFIRMED
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