BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Memento EPFL// BEGIN:VEVENT SUMMARY:Vision & Cognition Seminar // Anne Giersch - A disruption of the p rediction of sequences at the ms level in schizophrenia: a mechanism for a ltered immersion in the world? DTSTART:20190315T163000 DTEND:20190315T173000 DTSTAMP:20260405T200433Z UID:d6035ee7ac1875698bdc9eb5119e02fa116d11c1215d3cdbfd5f7322 CATEGORIES:Conferences - Seminars DESCRIPTION:Anne Giersch INSERM U1114\, University Hospital of Strasbour\n The feeling of being one continuous individual in time is a natural eviden ce\, which is disturbed in patients with schizophrenia\, who feel disconne cted from the environment. I will describe clinical reports suggesting a d isruption of the sense of time continuity in schizophrenia\, associated wi th a disruption of the sense of self\, and of the feeling of being immerse d in the world. I will show how we objectified timing disorders in patient s\, while trying to understand the mechanisms underlying the sense of time continuity. Patients are impaired at detecting asynchronies and ordering stimuli\, suggesting distortions in the temporal structure of consciousnes s. The amplitude of the impairments led us to explore timing at a non-cons cious level. We showed that in healthy subjects events are distinguished i n time automatically even when subjectively judged as being simultaneous. Our most recent data\, based on sequential effects\, suggests that sequenc es of future visual information are predicted and allow subjects to alloca te attention in the right place and right time. We will argue that a close synergy between non-conscious prediction of sequences and attention is ne cessary for the sense of immersion in the environment and the feeling of t ime continuity to emerge. Conversely\, both behavioral and EEG data sugges t that time prediction is impaired in patients with schizophrenia with bod ily self disorders\, and especially the production of sequences at the mil lisecond level. I will propose possible therapeutic developments for the p atients.\n  LOCATION:SV2510 STATUS:CONFIRMED END:VEVENT END:VCALENDAR