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SUMMARY:Molecular and nanoscale materials to study and modulate neural cir
 cuits
DTSTART:20190306T150000
DTEND:20190306T160000
DTSTAMP:20260509T234221Z
UID:103b754e5d3e1bb7b4c642b2e59ef17eaf990f9326cddf49fca3e7c5
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr Ritchie Chen\, Stanford University\, USA.\nDysfunctional ne
 uronal signaling underlies a wide range of psychiatric and neurological di
 sorders. Existing therapeutics often lack clinical efficacy to reverse sig
 naling imbalance and are both non-specific and invasive. To improve treatm
 ents of brain-related diseases will require new tools and methods to map a
 nd to repair the brain with precision and biocompatibility. In my talk\, I
  will demonstrate how rational design of materials at the molecular and na
 noscale enables new approaches to study functional and biomolecular inform
 ation across the brain\, and to modulate the activity of intact neural cir
 cuits with cell-type specificity. I will describe (1) the discovery of new
  multifunctional fixatives to render tissue transparent for mapping of cir
 cuit projections\, mRNA\, and proteins across the whole-brain\, and (2) th
 e engineering of magnetic nanoparticles to remotely evoke neural activity 
 without the need for wired implants. These results\, along with a discussi
 on of future synthetic neural interfaces\, aim to improve our understandin
 g of the nervous system and to inform new therapeutic approaches for bioel
 ectronics medicine.\n\nBio\nRitchie Chen is a postdoctoral fellow conducti
 ng systems neuroscience research at Stanford University with Professor Kar
 l Deisseroth. He received his PhD in Materials Science and Engineering fro
 m the Massachusetts Institute of Technology and a BS in Bioengineering fro
 m the University of California Berkeley. His research bridges materials en
 gineering with neuroscience to develop tools to better understand the nerv
 ous system. For his work on developing neurotechnology platforms\, he has 
 been awarded a Forbes 30 under 30 in Science and a Helen Carr Peake Resear
 ch Prize.\n\nVideo transmission using zoom : https://epfl.zoom.us/j/994649
 5775\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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