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SUMMARY:A computational approach to translational neuroscience
DTSTART:20190327T150000
DTEND:20190327T160000
DTSTAMP:20260414T071555Z
UID:ab657e3290fe81ab664f687ceb82e001655c8b1d230facd8abbfcaeb
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr Marco Capogrosso\, University of Fribourg\, CH.\nTraumatic 
 injuries and diseases of the motor system affect millions of people worldw
 ide. Only in Europe approximately 3 million people are affected by the con
 sequences of spinal cord injury\, stroke and multiple sclerosis\, for a to
 tal estimated healthcare cost of 45 billion euros per year. Treatments for
  these conditions are needed to ease both their growing economic and socie
 tal impact. Recent advances in neurotechnologies and brain machine interfa
 ces have prompted promising results in laboratory settings. However\, none
  of these approaches translated into actual clinical solutions to motor pa
 ralysis. Specifically\, the scarce knowledge on the mechanisms of neural c
 ontrol of movement hinder the design of effective neurotechnologies thus l
 imiting their usability for people with severe disabilities. Here present 
 a computational and technological framework to understand how damaged neur
 al circuits can use electrical stimulation inputs for correcting aberrant 
 motor behaviors. I will then show how to use this knowledge to design and 
 test novel neurotechnologies enhancing motor recovery after paralysis.\n 
 \nBio\nMy main interest is the understanding of the neural control of move
 ment with a focus on translational applications in motor disorders. I have
  a background in applied physics and PhD in Biomedical Engineering from th
 e Scuola Superiore Sant'Anna\, in Pisa. Since my PhD under the supervision
  of Prof. Silvestro Micera\, and during my Post-Doc at EPFL hosted by Prof
 . Gregoire Courtine I have worked towards the definition of a computationa
 l framework for the design of neuroprosthetics. My models revealed the neu
 ral targets of epidural electrical stimulation of the spinal cord (Journal
  of Neuroscience.\, Neuron) and currently represent the generally accepted
  model of epidural stimulation by the international community. I have then
  translated the concepts that my models outlined in rats to Rhesus monkeys
  and developed a technology that linked motor related signals from the bra
 in to stimulation protocols applied at the lumbar spinal cord. These proto
 cols and technologies restored locomotion in monkeys with spinal cord inju
 ry as early as 6 days after lesion (Nature). In 2016 I obtained a SNSF Amb
 izione grant at the University of Fribourg where I established an advanced
  experimental platform for motor neuroscience in nonhuman primates. I am c
 urrently developing Brain Computer Interfaces and electrical stimulation s
 trategies for the recovery of arm and hand movements after spinal cord inj
 ury. Ultimately\, I love science.\n\nVideo transmission using zoom : https
 ://epfl.zoom.us/j/9946495775
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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