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SUMMARY:Computational Neuroscience Seminar: Tiziano D'Albis
DTSTART:20190319T140000
DTEND:20190319T150000
DTSTAMP:20260924T170145Z
UID:4b6da1d6234f7178a4e319ebc37f580f731863d0d791bc075bbb983c
CATEGORIES:Conferences - Seminars
DESCRIPTION:Tiziano D'Albis\nTitle: The origin\, inheritance\, and amplifi
 cation of grid-cell patterns\n\nAbstract: Grid cells are neurons of the me
 dial entorhinal cortex that fire according to the position of an animal in
  its environment. A single grid cell activates at multiple spatial locatio
 ns with firing fields that form a regular triangular pattern. Grid cells a
 re thought to support animal's navigation and spatial memory\, but the mec
 hanisms that generate their patterns are still unknown. In this talk\, I p
 resent a theory that explains the emergence\, inheritance\, and amplificat
 ion of grid-cell activity.\nFirst\, I focus on the emergence of spatial pa
 tterns. I embrace the idea that periodic representations of space could em
 erge via a competition between persistently-active inputs and the reluctan
 ce of a neuron to fire for long stretches of time. Building upon previous 
 theoretical work\, I propose a single-cell model that generates grid-like 
 activity solely form spatially-irregular inputs\, spike-rate adaptation\, 
 and Hebbian synaptic plasticity.\nIn the second part of my talk\, I focus 
 on the inheritance and amplification of grid-cell patterns. I show that gr
 ids can be inherited across neuronal populations\, and that both feed-forw
 ard and recurrent connections can amplify the regularity of spatial firing
 . Finally\, I show that a connectivity supporting these functions could se
 lf-organize in an unsupervised manner.\nAltogether my work aims at underst
 anding the fundamental principles governing the neuronal representation of
  space in the medial entorhinal cortex.
LOCATION:CO 121
STATUS:CONFIRMED
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