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SUMMARY:[ MICHAEL J. FOX FOUNDATION - Biology of Astrocytes in Parkinson
 ’s Disease | Research funding ]
DTSTART;VALUE=DATE:20190419
DTSTAMP:20260916T034811Z
UID:6d0e4634a5efa4941090a7ce784a95abe420ff34eb644956d2e50519
CATEGORIES:Call for proposal
DESCRIPTION:Aim: The Michael J. Fox Foundation will award one-year to 18-m
 onth grants for studies that explore the role of astrocytes in Parkinson
 ’s disease (PD) pathology and the potential for astrocyte-focused therap
 eutics. The goals of this funding program are to further understanding of 
 astrocyte biology in Parkinson’s and to rationalize the pursuit of astro
 cyte-specific targets and/or pathways for the treatment of the disease.\n
  \nPreference will be given to applications that focus on or include the 
 following:\n\n	Role of astrocytes in initiating and/or propagating Parkins
 on’s disease pathology\, including alpha-synuclein spread\, dopaminergic
  neuron death\, inflammation and senescence\n	Consequences of dysfunction 
 and/or mutations of common PD targets\, including alpha-synuclein\, LRRK2\
 , GBA\, PRKN and PINK1\n	Manipulation of astrocyte activity and/or astrocy
 te-specific pathways to assess the potential of targeted astrocyte therapi
 es on disease biology and/or symptoms\n	Parkinson’s disease models with 
 high construct validity to human PD\, including patient-derived material (
 such as iPSCs or cerebral organoids) and/or well characterized animal mode
 ls and primary cells\; Examination of human brain samples to answer specif
 ic hypotheses is also acceptable\n	Targets\, pathways and mechanisms propo
 sed for investigation should have reasonable links to PD.\n\n \nFunding: 
        Maximum USD $150’000\n                  
      \nDuration:      12-18 months\n              
          \nEligibility: Researchers at all academic levels at or 
 above Assistant Professor are eligible to apply. Post-doctoral fellows are
  eligible to apply as co-investigators with the designation of an administ
 rative primary investigator who directs the laboratory in which the fellow
  will conduct research.\n \nHow to Apply: The pre-proposal is the first s
 tep in the application. Pre-proposals must be completed in the online appl
 ication portal.  Successful applicants will be given further instructions
  for submitting a full proposal.\n \nDeadline (Pre-proposal): 19 April 20
 19 (5:00 pm EST)\nDeadline (Full Application\, by invitation): 19 July 201
 9 (5:00 pm EST)\n \nFurther information\n\n\n	See the official webpage f
 or more details\, or download the RFA\n	Find the application portal\n	Part
 icipate in the MJFF funding opportunities webinar on 01 April to learn mor
 e\n	For any other questions\, contact the Research Office: research@epfl.c
 h\n
LOCATION:
STATUS:CONFIRMED
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