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SUMMARY:Circuits and Behavior Seminar // Information coding and calcium dy
 namics at hippocampal mossy fibre synapses
DTSTART:20190611T163000
DTEND:20190611T173000
DTSTAMP:20260407T014746Z
UID:04d4f7b0add4e5a405a6a82f17d36728f2da9380923255cb017fd60c
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Katalin Tóth\, CERVO Brain Research Centre\, Universi
 té Laval\, Québec\nNeurons in the entorhinal cortex and the hippocampus 
 respond to distinct spatial locations and other parameters essential to bu
 ild and memorize navigational clues. Cortical information is translated t
 o hippocampal code by granule cells. Their synapses\, form large complex t
 erminals that operate with multiple release sites. Research in my laborato
 ry is focused on the mechanism by which these terminals code incoming sign
 als and translate it to a particular pattern of neurotransmitter release.
  Are distinct release sites functionally diverse or uniform? We aim to 
 unveil the functional relevance of their heterogeneity in information tran
 sfer at complex synapses. We investigate these questions in in vitro hipp
 ocampal slices and use morphological (electron microscopy)\, electrophysio
 logical (patch-clamp)\, imaging (two-photon imaging) and computational app
 roaches at the level of individual synapses. 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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