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SUMMARY:ENAC Seminar Series by Prof. P. Vikesland
DTSTART:20190627T130000
DTEND:20190627T140000
DTSTAMP:20260917T091912Z
UID:e2127d5843d8a77cf480970f8dca223806d47c0447d5c3af66383ddf
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. P. Vikesland\n13:00 – 14:00 – Prof. Peter Vikesland 
 \nFull Professor\, Civil & Environmental Engineering\, Virginia Tech\, USA
 \n\nBioNanoTechnology Enabled Environmental Sensing     \n\nAchieving glob
 al sustainability is one of the greatest challenges of our time\, and crit
 ical to attainment of this goal is the continual protection of air and wat
 er. To assure the quality of these matrices\, we currently rely upon a bro
 ad range of monitoring techniques - many of which are outdated and unrelia
 ble. However\, recent advances in both nanotechnology and biotechnology ar
 e enabling development of novel sensor platforms that are more sensitive a
 nd more cost-effective than existing approaches. In this presentation\, I 
 will illustrate how these new sensor technologies can be used both for hig
 hly targeted analyte detection as well as for non-target analyses.\n \nIn
  the first part of this presentation\, I will present work conducted to de
 velop gold nanoparticle enabled plasmonic platforms that facilitate target
 ed analyte detection.  As will be shown\, surface enhanced Raman spectros
 copy (SERS) can be used to sensitively detect and quantify a broad array o
 f environmental analytes such as pathogens\, pharmaceuticals\, and pH both
  in bulk samples as well as in confined environments. Such quantitation is
  achieved through the application of a new quantitative approach entitled 
 ‘Hot-Spot Normalized SERS’.\n \nIn the second part of the presentatio
 n\, I will illustrate the power of non-targeted metagenomic sequencing met
 hods to delineate the ‘resistomes’ of wastewaters collected from acros
 s the world. Antibiotic resistance is a global public health concern compr
 ising multiple environmental pathways whereby emergence\, horizontal trans
 fer\, dissemination and human exposure routes are supported. Wastewater tr
 eatment plants are one such pathway as they provide an ideal environment f
 or the convergence of pathogenic and non-pathogenic resistance carriers\, 
 antibiotic resistance genes (ARGs) and selective pressures\; while also pr
 oviding ample opportunity for horizontal and vertical gene transfer. I wil
 l show how a combination of approaches including Illumina and Nanopore seq
 uencing\, SERS\, and data analytics provide complementary insights about t
 his emerging global threat.
LOCATION:BC 420 https://plan.epfl.ch/?room==BC%20420
STATUS:CONFIRMED
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