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SUMMARY:Emerging imaging technologies to study cell architecture\, dynamic
 s and function
DTSTART:20191008T110000
DTSTAMP:20260501T142008Z
UID:e6a693332a259723284cdce7494e3356324ebf63c153869c4af87ebf
CATEGORIES:Conferences - Seminars
DESCRIPTION:Jennifer Lippincott-Schwartz\, Janelia Research Campus\, HHMI\
 , Ashburn\, VA\nPowerful new ways to image the internal structures and com
 plex dynamics of cells are revolutionizing cell biology and bio-medical re
 search.\n\nIn this talk\, I will focus on how emerging fluorescent technol
 ogies are increasing spatio-temporal resolution dramatically\, permitting 
 simultaneous multispectral imaging of multiple cellular components. In add
 ition\, results will be discussed from whole cell milling using Focused Io
 n Beam Electron Microscopy (FIB-SEM)\, which reconstructs the entire cell 
 volume at 4 voxel resolution.\n\nUsing these tools\, it is now possible to
  begin constructing an “organelle interactome”\, describing the interr
 elationships of different cellular organelles as they carry out critical f
 unctions. The same tools are also revealing new properties of organelles a
 nd their trafficking pathways\, and how disruptions of their normal functi
 ons due to genetic mutations may contribute to important diseases.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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