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SUMMARY:Absorption of low energy UV radiation by DNA: excited states and r
 eactivity
DTSTART:20191003T171500
DTEND:20191003T181500
DTSTAMP:20260919T120305Z
UID:ff7cbf7144980c1b249fcc184b3c2f96df79e977ead0778a9f9818d5
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr. Dimitra Markovitsi\nLIDYL\, CEA\, CNRS\, Université Paris
  Saclay\nFrance\nThe objective of the study is to (i) understand the prima
 ry events involved in the damage of the genetic code provoked by UV radiat
 ion and (ii) determine the factors governing the optical properties of DNA
 -inspired materials.\n\nThe seminar will focus on the processes occurring 
 when low energy UV photons (l>230 nm) are absorbed directly by DNA. It wil
 l present a picture arising from results obtained in this field since the 
 beginning of the 21st century by optical spectroscopy and theoretical chem
 istry and highlight important challenges lying ahead.\nRepresentative exam
 ples related to photon absorption\, excited state relaxation and chemical 
 reactions (base dimerization and radical generation) will be given.\nFinal
 ly\, the contribution of in vitro spectroscopic studies\, compared to biol
 ogical in vivo investigations will be highlighted.\n \n 
LOCATION:BCH 2201 https://plan.epfl.ch/?room==BCH%202201
STATUS:CONFIRMED
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