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SUMMARY:Attenuating oncogenic transcription with small molecules
DTSTART:20200611T121500
DTEND:20200611T133000
DTSTAMP:20260510T053659Z
UID:138f7ebd0cb862d880c95d9d204d5e818492f83e873ac852f93f7c1a
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Angela KOEHLER Goldblith Career Development Professor in
  Applied Biology Department of Biological Engineering MIT Koch Institute f
 or Integrative Cancer Research MIT MIT Center for Precision Cancer Medicin
 e Cambridge\, MA - USA\nA Lola and John Grace Distinguished Lecture in Can
 cer Research\nThis seminar will also be televised to AGORA Auditorium Pate
 rnot + Biopôle B301/CLE + Geneva University-CMU Auditorium Paul Boymond B
 02.226\n\nAngela Koehler is the Goldblith Career Development Professor in 
 Applied Biology in the Department of Biological Engineering at MIT and an 
 intramural member of the David H. Koch Institute for Integrative Cancer Re
 search at MIT. She is also an Institute Member of the Broad Institute and 
 a Founding Member of the MIT Center for Precision Cancer Medicine. Her res
 earch group aims to discover and develop functional small-molecule probes 
 of transcriptional regulators\, including chromatin modifying enzymes and 
 oncogenic transcription factors. Validated probes may be used to advance t
 he understanding of transcription in development and disease. Selected pro
 bes may be developed into imaging agents\, diagnostic tools\, or therapeut
 ic leads.\n\nAngela received her B.A. in Biochemistry and Molecular Biolog
 y from Reed College in 1997. There she worked under the guidance of Profes
 sor Arthur Glasfeld on structural and biochemical studies of proteins that
  recognize tRNA or DNA. In 2003\, she received her Ph.D. in Chemistry from
  Harvard University where she worked with Professor Stuart Schreiber to de
 velop novel technologies for identifying and characterizing interactions b
 etween proteins and small molecules. Upon graduation\, she became an Insti
 tute Fellow in the Chemical Biology Program at the Broad Institute and a G
 roup Leader for the NCI Initiative for Chemical Genetics.\n\nAt MIT\, Ange
 la serves at the Faculty Director of the High-Throughput Sciences Facility
  in the Swanson Biotechnology Center. She is also a co-Director of the MIT
  Biomedical Engineering Undergraduate Program and a member of the Committe
 e on Pre-Health Advising. Angela has served on the Chemists in Cancer Rese
 arch Executive Advisory Board for AACR. Awards include being named a Genom
 e Technology Young Investigator and a Broad Institute Merkin Fellow as wel
 l as the Novartis Lectureship in Chemistry\, the Ono Pharma Breakthrough S
 cience Award\, the AACR-Bayer Innovation and Discovery Award and the Junio
 r Bose Award for Excellence in Teaching. Angela serves as a consultant or 
 scientific advisory board member to several pharmaceutical or biotechnolog
 y companies and has founded two biotechnology companies.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CANCELLED
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