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SUMMARY:Dietary Control of Stem Cells in Physiology and Disease
DTSTART:20191219T141500
DTEND:20191219T151500
DTSTAMP:20260427T195312Z
UID:1e1c1aab086cc25258e04c1746bc4924b2236e9a343925adaaa1a23d
CATEGORIES:Conferences - Seminars
DESCRIPTION:Professor Ömer H. Yilmaz\, MD\, PhD\, Koch Institute for In
 tegrative Cancer Research at MIT and Massachusetts General Hospital\, Harv
 ard Medical School\, Cambridge\, MA\, United States\nBIOENGINEERING SEMIN
 AR\n \nAbstract:\nOrganismal diet has a profound impact on tissue homeost
 asis and health in mammals. Adult stem cells are a keystone of tissue adap
 tation that alter tissue composition by balancing self-renewal and differe
 ntiation divisions. Because somatic stem cells may respond to organismal 
 physiology to orchestrate tissue remodeling and some cancers are understoo
 d to arise from transformed stem cells\, these findings raise the possibil
 ity that organismal diet\, stem cell function\, and cancer initiation are 
 interconnected. Here I will present work from my group that describes our 
 emerging view of how diet\, metabolites and nutrient-sensing pathways inst
 ruct mammalian intestinal stem cell fate in homeostasis\, adaptation to d
 iet and diseases such as cancer.\n\nBio:\nÖmer Yilmaz is the Eisen and Ch
 ang Career Development Associate Professor of Biology at the Koch Institut
 e for Integrative Cancer Research at MIT and a gastrointestinal pathologis
 t at the Massachusetts General Hospital and Harvard Medical School. He is 
 a graduate of the University of Michigan Medical School\, where he perform
 ed his thesis work under the guidance of Professor Sean Morrison. He has a
 lso spent three years as a Postdoctoral Fellow in the laboratory of Profes
 sor David M. Sabatini\, a member of the Whitehead and Koch Institutes. In 
 2014 he established his lab\, which focuses on understanding how intestina
 l stem cells and their microenvironment adapt to diverse diets in the cont
 ext of tissue regeneration\, aging\, and cancer initiation/progression. Hi
 s achievements\, to date\, have been recognized with a Harold Weintraub Aw
 ard (2007)\, a V Scholar Award (2015)\, a Pew-Stewart Trust Fellowship (20
 16)\, a Sidney Kimmel Fellowship (2016)\, a Sabri Ulker International Scie
 nce Prize (2018)\, and AAAS Martin and Rose Wachtel Cancer Research Prize 
 (2018). 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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