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SUMMARY:Prof. Kenji Doya: “Patience\, Confidence and Serotonin”
DTSTART:20191111T150000
DTEND:20191111T160000
DTSTAMP:20260928T184118Z
UID:595be87e77637524565ae9ac5d7d507724cc5e5d89267ebedf92f565
CATEGORIES:Conferences - Seminars
DESCRIPTION:Abstract\nKenji Doya\, Kayoko W Miyazaki\, Katsuhiko Miyazaki\
 nNeural Computation Unit\, Okinawa Institute of Science and Technology Gra
 duate University\, Japan\n \nEvaluation of delayed reward is an essential
  component of rational decision making. We hypothesized that the brain’s
  serotonergic system regulates the temporal discounting of future rewards.
  Human brain imaging experiments showed that different cortico-basalgangli
 a loops are involved in reward prediction in different time scales and tha
 t they are differentially modulated by serotonerin. Chemical recording and
  manipulation in rats showed that serotonin release is elevated when anima
 ls are engaged in delayed reward tasks and that suppression of dorsal raph
 e serotonin neurons increase reward waiting errors. Electrode recording of
  dorsal raphe neurons revealed that their firing increases during reward w
 aiting period and drops just before the animal abandons waiting. Optogenet
 ic activation of dorsal raphe serotonin neurons reduced waiting errors and
  extended waiting time in reward omission trials\, but the effect was crit
 ically dependent on the probability and timing of reward delivery. These r
 esults suggest that the dorsal raphe serotonergic projection affects the p
 atience for delayed rewards by modulating the confidence in the delivery o
 f future reward.\nBio\nKENJI DOYA took BS in 1984\, MS in 1986\, and Ph.D.
  in 1991 at U. Tokyo. He became a research associate at U. Tokyo in 1986\,
  U. C. San Diego in 1991\, and Salk Institute in 1993. He joined Advanced 
 Telecommunications Research International (ATR) in 1994 and became the hea
 d of Computational Neurobiology Department\, ATR Computational Neuroscienc
 e Laboratories in 2003. In 2004\, he was appointed as the Principal Invest
 igator of Neural Computation Unit\, Okinawa Institute of Science and Techn
 ology (OIST) and started Okinawa Computational Neuroscience Course (OCNC) 
 as the chief organizer. As OIST established itself as a graduate universit
 y in 2011\, he became a Professor and served as the Vice Provost for Resea
 rch till 2014. He serves as the Co-Editor in Chief of Neural Networks sinc
 e 2008 and a board member of Japanese Neural Network Society (JNNS) and Ja
 pan Neuroscience Society (JNSS). He served as the Program Co-Chair of Inte
 rnational Conference on Neural Information Processing (ICONIP) in 2007 and
  2016\, the Program Chair of JNSS meeting in 2010\, and the General Chair 
 of JNNS meeting in 2011 and 2018. He received Tsukahara Award and JSPS Awa
 rd in 2007\, MEXT Prize for Science and Technology in 2012\, Donald O. Heb
 b Award in 2018\, JNNS Academic Award in 2019\, and the age-group 2nd plac
 e at Ironman Taiwan in 2019. He lead the MEXT project “Prediction and De
 cision Making” from 2011 to 2016 and currently leads a new MEXT project 
 “Artificial Intelligence and Brain Science”. He is interested in under
 standing the functions of basal ganglia and the cortical circuit based on 
 the theory of reinforcement learning and Bayesian inference.\nContact: doy
 a@oist.jp\, Neural Computation Unit\, Okinawa Institute of Science and Tec
 hnology Graduate University\, 1919-1 Tancha\, Onna\, Okinawa 904-0495\, Ja
 pan.\n 
LOCATION:B1 6 259.054 https://plan.epfl.ch/?room==B1%206%20259.054
STATUS:CONFIRMED
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