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SUMMARY:BMI SEMINAR - Webinar //  Patrik Verstreken - The cellular basis o
 f Parkinson’s disease
DTSTART:20201007T121500
DTEND:20201007T131500
DTSTAMP:20260427T214915Z
UID:e93f39abbbd79b62f9aa377ba28fb7387310e8710a17a6bca3d090b5
CATEGORIES:Conferences - Seminars
DESCRIPTION:Patrik Verstreken\, VIB-KU Leuven Center for Brain & Disease R
 esearch\, Leuven\, Belgium\nParkinson’s disease is affects millions of p
 eople around the world.  The disease is characterized by typical movement
  defects that are caused by the loss of dopaminergic neurons\, but several
  very debilitating non-motor symptoms occur more than 10 years before the 
 motor symptoms.  I will discuss how we study these non-motor symptoms inc
 luding sleep disturbances and olfactory defects using large collections of
  knock in fruit flies that model the numerous familial forms of Parkinson
 ’s disease as well as using human iPS cells from patients.  A common em
 erging theme are defects in protein homeostasis that in specific neuronal 
 cell types\, cause cellular defects that explain the Parkinson-relevant ph
 enotypes.  Our work reveals the mechanisms that cause early defects in Pa
 rkinson’s disease and it opens therapeutic avenues to start tackling thi
 s disease.\n 
LOCATION:Online https://epfl.zoom.us/j/319958825
STATUS:CONFIRMED
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