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SUMMARY:Lymphatic vessels and their roles in shaping the tumor immune micr
 oenvironment
DTSTART:20201119T121500
DTEND:20201119T133000
DTSTAMP:20260429T195350Z
UID:aba79fca48ec3658942d12d09e3563536d050e7ce033d3b8da94e0de
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Melody SWARTZ Swartz Group   Pritzker School of Molecul
 ar Engineering - The University of Chicago - USA\nA Lola and John Grace Di
 stinguished Lecture in Cancer Research\nThis seminar will also be televise
 d to CHUV/AGORA\, Biopôle and Geneva University (rooms tbc)\n \nSwartz
 ’s research focuses on elucidating and exploiting the roles of lymphatic
  function as it relates to cancer and chronic inflammatory diseases includ
 ing asthma\, using a variety of interdisciplinary approaches from bioengin
 eering\, immunobiology\, physiology\, cell biology and biomechanics. Her l
 ab works in both basic hypothesis-driven research as well as in translatio
 nal applications. A major interest has been to understand the immunologica
 l implications of lymphangiogenesis in tumors and other chronic inflammato
 ry conditions\, including allergic airway disease. Other current projects 
 include elucidating new immunological functions of lymphatic endothelium a
 nd developing novel strategies for targeting the lymphatics and sentinel l
 ymph nodes for immunotherapy. Building novel\, physiologically relevant\, 
 3D model systems for recapitulating key features of interest in tumor and 
 lymphatic microenvironments has been an integral part of this research pro
 gram\, and they use those models in complementary ways with mouse models t
 o gain new insight into tumor cell invasion and metastasis. \n\n\nMelody 
 A. Swartz is the William B. Ogden Professor in the Pritzker School of Mole
 cular Engineering at the University of Chicago\, where she holds a joint 
 appointment in the Ben May Department for Cancer Research. She obtained he
 r BS from Johns Hopkins and PhD from MIT\, both in Chemical Engineering\, 
 and carried out postdoctoral work at Harvard Medical School and the Brigha
 m & Women’s Hospital. She started her independent career as an Assistant
  Professor at Northwestern University in the Department of Biomedical Engi
 neering before moving to the Ecole Polytechnique Fédérale de Lausanne (E
 PFL)\, where she was promoted to Full Professor and eventually served as D
 irector of the Institute of Bioengineering.  Trained as a bioengineer\, s
 he uses quantitative approaches in immunobiology and physiology\, includin
 g biotransport and biomechanics\, to develop a deeper understanding of how
  the lymphatic system regulates immunity in homeostasis and disease\, part
 icularly in cancer and chronic inflammation. Her lab applies this knowledg
 e to develop novel immunotherapeutic approaches in cancer\, including lymp
 h node-targeting vaccine approaches\, as well as in vitro model systems th
 at recapitulate relevant features of the tumor-immune interface. Among her
  many honors\, Swartz was named a MacArthur Fellow in 2012\, and was elect
 ed to the National Academy of Arts and Sciences in 2018.
LOCATION:Room TBC
STATUS:CANCELLED
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