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SUMMARY:Computational Design of Self-Assembling Peptides and Proteins
DTSTART:20191206T100000
DTEND:20191206T110000
DTSTAMP:20260508T103628Z
UID:52adee0c56318ab7cc813ba2c7381bc55592c0df7accada55e73e737
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Ingemar André\, Lund University (SE)\nBIOENGINEERING SE
 MINAR    \n\nAbstract:\nMany of the largest protein complexes in biolo
 gy are composed of a single type of subunit that is repeated a large numbe
 r of times to generate a functional assembly. Such homomeric structures ar
 e often assembled spontaneously from individual components through the pro
 cess of self-assembly. Research in our group is focused on the prediction 
 of the three-dimensional structure of homomeric assemblies and the rationa
 l design of novel self-assembling proteins and peptides. I will demonstrat
 e how protein design can be used to develop a self-assembling protein cont
 ainer system for selective encapsulation of proteins. I will also describe
  the development of a peptide with a pH dependent oligomerization switch\,
  with applications as pH sensitive control elements that can control assem
 bly of larger proteins.
LOCATION:AI 1153 https://plan.epfl.ch/?room==AI%201153
STATUS:CONFIRMED
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