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SUMMARY:BioE COLLOQUIA SERIES: "Advanced In Vitro Platforms for Respirator
 y Research in Bridging In Vivo Interfaces" - via web streaming only (Covid
 -19 situation)
DTSTART:20200427T121500
DTEND:20200427T131500
DTSTAMP:20260929T061548Z
UID:841288c80cba38ab5cabc026d252af7be584772601c36046a4bc5c33
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Josué Sznitman\, Technion – Israel Institute of Techn
 ology\, Haifa (IL)\nWEEKLY BIOENGINEERING COLLOQUIA SERIES\n\n\nAbstract:\
 nThe development of lung-on-chips is providing new avenues for more realis
 tic inhalation assays in research and thus an opportunity to depart from t
 raditional in vitro lung assays. As advanced models capturing the cellular
  pulmonary make-up at an air-liquid interface (ALI)\, lung-on-chips emulat
 e both morphological features and biological functionality of the airway b
 arrier with the ability to integrate respiratory breathing. These in vitro
  systems allow importantly to mimic more realistic physiological respirato
 ry flow conditions\, with the opportunity to integrate physically-relevant
  transport determinants of aerosol inhalation therapy\, i.e. recapitulatin
 g the pathway from airborne flight to deposition on the airway lumen. Here
 \, we will discuss such advances and describe how these attributes are pav
 ing new avenues for exploring improved drug carrier designs (e.g. shape\, 
 size\, etc.) and targeting strategies (e.g. conductive vs. respiratory reg
 ions) amongst other. While technical challenges still lie along the way in
  rendering in vitro lung-on-chip platforms more widespread across the gene
 ral pharmaceutical research community\, significant momentum is steadily u
 nderway in accelerating the prospect of establishing these as in vitro "go
 ld standards".\n\nBio:\nJosué Sznitman is a Swiss\, French and Israeli na
 tional. Sznitman graduated from MIT (2002)\, followed by a Dr. Sc. (2008) 
 from ETH Zurich. In 2008\, Sznitman joined UPenn as a Postdoctoral Fellow 
 and moved to Princeton University as a Lecturer and Research Associate. He
  joined the Department of Biomedical Engineering at the Technion in 2010 a
 s a tenure-track Assistant Professor and was promoted to Associate Profess
 or with tenure in 2016. Sznitman currently serves as Associate Chair for U
 ndergraduate Studies in the Department of Biomedical Engineering and is th
 e Director of the Norman Seiden Graduate Program in Nanoscience & Nanotech
 nology. As a researcher\, he directs the Technion Biofluids Laboratory. Sz
 nitman was awarded the Young Investigator Award (2015) by the Internationa
 l Society of Aerosols in Medicine (ISAM) for a researcher under 40 and mos
 t recently the 2018 Emerging Scientist Award in Drug Delivery to the Lungs
  (Aerosol Society\, UK). He serves as Associate Editor of Clinical Biomech
 anics\, is a member of the Editorial Board of Biomicrofluidics and Journal
  of Biomechanics\, and serves as Academic Editor of PLoS One. Between 2015
  and 2019\, he served as Committee Member and Coordinator of Short Term Sc
 ientific Missions (STSM) in the COST Action MP 1404 (SimInhale). Sznitman 
 has been a recipient of European funding schemes including an FP7 Career I
 ntegration Grant (CIG)\, a European Research Council (ERC) Starting Grant 
 (StG) and a Proof-of-Concept (PoC) Grant. His recent dissemination activit
 ies have included Webinars and a TEDx Talk (2019) titled “From race cars
  to the lungs” (available at: https://youtu.be/7IDfqlvWSU8).\n\n\nZoom l
 ink for attending remotely: https://epfl.zoom.us/j/98981744542\n\nIMPORTAN
 T NOTICE: this seminar can be followed via Zoom web-streaming only (link a
 bove)\, due to restrictions resulting from the ongoing Covid-19 situation.
LOCATION:via Zoom web-streaming only\, due to Covid-19 situation https://e
 pfl.zoom.us/j/98981744542
STATUS:CONFIRMED
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