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SUMMARY:Mucosal immunity in the bladder
DTSTART:20200225T121500
DTSTAMP:20260507T182852Z
UID:91de6e52baf46050c5e4b60eb9a0cf49073e216130f8674729cbd3c6
CATEGORIES:Conferences - Seminars
DESCRIPTION:Molly Ingersoll\, Institut Pasteur\nAbstract: Urinary tract in
 fections (UTI) are the second most common infection\, impacting nearly 50%
  of all women. Indeed\, otherwise healthy\, premenopausal women have a sig
 nificantly greater incidence of urinary tract infection (UTI) than men\, y
 et\, conversely\, male UTI is more persistent with greater associated morb
 idity. Additionally\, both sexes are at significant risk of reinfection\, 
 suggesting that adaptive immune responses to this infection are insufficie
 nt. Our group is interested in identifying the mechanisms that govern sex 
 bias and development of immunity in UTI. Our recent work demonstrates that
  resident macrophages impair the adaptive response and that IL-17 is a cri
 tical player in resolution of infection. Currently\, we are dissecting the
  initial events leading to a specific effector cell response and how this 
 response can be immunomodulated for improved therapeutics that obviate the
  need for antibiotics to treat multidrug resistant uropathogens.\n\nBio: D
 r. Molly Ingersoll received her PhD studying host-pathogen interactions fr
 om NYU School of Medicine working with Arturo Zychlinsky at NYU and at the
  Max Planck Institute for Infection Biology in Berlin\, Germany. A brief p
 ostdoctoral fellowship at Washington University School of Medicine\, in St
  Louis\, MO with Scott Hultgren\, studying innate immunity to urinary trac
 t infection was followed by a postdoctoral appointment at Mount Sinai Medi
 cal Center in NYC\, investigating monocyte and dendritic cell biology. Dr.
  Ingersoll is a Group Leader with a team interested in immunity in the bla
 dder in the context of infection and cancer at the Institut Pasteur in Par
 is.\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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