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SUMMARY:Mitochondrial dynamics in health and disease
DTSTART:20200227T110000
DTEND:20200227T120000
DTSTAMP:20260601T011636Z
UID:90981ca86b9d531c1f75b8ac2d42436fd3de9d5d44892e5f614d6b29
CATEGORIES:Conferences - Seminars
DESCRIPTION:Thimoty Wai (PhD) CNRS – Institut Pasteur\, Paris\, Biologie
  mitochondriale\, Département de Biologie cellulaire et infection     
    \nThe research focus of the lab is to understand the relevance of mit
 ochondrial dynamics in health and disease.  The morphology of mitochondri
 a is inextricably linked to its many essential functions in the cell and w
 e are interested in understanding the relationship between mitochondrial s
 hape changes and metabolism in the context of acquired and inborn human di
 seases.  I will discuss ongoing work using genetic screens to identify fa
 ctors novel regulators and modulators of mitochondrial morphology in cells
  from patients with mitochondrial genetic diseases and the lessons we are 
 learning regarding the importance of balanced mitochondrial dynamics.  I 
 will also discuss the relevance of mitochondrial fission in cardiac metabo
 lism and the connections between mitochondria\, cell death\, inflammation 
 and heart failure in novel models developed by our lab.
LOCATION:BSP 407 https://plan.epfl.ch/?room==BSP%20407
STATUS:CONFIRMED
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