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SUMMARY:Optical modulation of membrane protein function in living samples
DTSTART:20200219T110000
DTEND:20200219T120000
DTSTAMP:20260407T051124Z
UID:7cac76c0de6dd809ee401673db5f83c58c0832d780ec5b2d2eabf2d9
CATEGORIES:Conferences - Seminars
DESCRIPTION:Mizuki Endo (Phd)  Department of Chemistry\, School of Science
 \, The University of Tokyo\, Japan\nIn multicellular organisms\, living ce
 lls cooperate with each other to exert coordinated complex functions by re
 sponding to extracellular chemical or physical stimuli via proteins on the
  plasma membrane. Conventionally\, chemical or physical signal transductio
 n have been investigated by chemical\, genetic\, or physical perturbation\
 ; however\, these methods cannot manipulate biomolecular reactions at high
  spatio-temporal resolution\, or provide molecular information. Here\, I p
 resent optogenetic systems that enable functional modulation of receptor p
 rotein activites with external light. The system enabled spatiotemporal mo
 dulation of various biological phenomena\, such as axon guidance and cell-
 cell tension transfer.\n 
LOCATION:BSP 231 https://plan.epfl.ch/?room==BSP%20231
STATUS:CONFIRMED
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