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SUMMARY:"Dendrites of human neurons: old bugs and new features"
DTSTART:20200513T110000
DTEND:20200513T120000
DTSTAMP:20260916T034808Z
UID:f85aecf9918f090f70540e290c8c2bebf27bd83db956cc26c830b837
CATEGORIES:Conferences - Seminars
DESCRIPTION:Albert Gidon PhD\, Humboldt-Universität zu Berlin\, Germany\n
 Abstract: In comparison to other mammalian species\, layers 2 and 3 of th
 e human cerebral cortex are disproportionately thick. Consequently\, the p
 yramidal neurons in these layers have large and elaborated dendritic trees
 . We studied the physiology of these dendrites and found that a "bug" prev
 iously described in rodents\, where distal dendritic inputs are severely a
 ttenuated at the soma\, is even worse in human dendrites. We also discover
 ed a new feature – dendritic calcium-mediated action potentials (dCaAPs)
 . In my talk\, I will discuss the unique properties of these dendrites and
  the consequences for the computational complexity emerging from their act
 ive properties.\n\nBio: I completed my undergraduate in the Hebrew Univer
 sity of Jerusalem (HUJI) studying biology. Then\, I did my Masters on mode
 ling synaptic plasticity in dendritic\, and PhD on the theory of synaptic 
 inhibition in dendrites\, both with Idan Segev in the HUJI. In this time\,
  I also worked in close collaboration with the Blue Brain Project on the m
 odeling of cortical neurons. In 2013\, I started my postdoc with Matthew L
 arkum where finally I started to electrically record and image dendrites o
 f cortical neurons from human and rodent brains with the aim to study the 
 biophysical building blocks that constitute the algorithms of cellular fun
 ction.\n\nThe Zoom link entitles you to exclusive participation to the sem
 inar. Please\, do not share the link with unauthorized third parties.
LOCATION:Zoom https://epfl.zoom.us/j/4283114565
STATUS:CONFIRMED
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