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SUMMARY:EPFL Neuro Seminar // Erin Schuman - Translation at the Synapse
DTSTART:20220601T160000
DTEND:20220601T170000
DTSTAMP:20260916T032120Z
UID:734dd0d50b29b55cb172ba93306c3b641bc22934c9278b846c5eb2d5
CATEGORIES:Conferences - Seminars
DESCRIPTION:Erin Schuman\, Max Planck Institute for Brain Research\, Germa
 ny\nThe complex morphology of neurons\, with synapses located hundreds of 
 microns from the cell body\, necessitates the localization of important ce
 ll biological machines\, including ribosomes\, within dendrites and axons.
  Local translation of mRNAs is important for the function and plasticity o
 f synapses. Using advanced sequencing and imaging techniques we have updat
 ed our understanding of the local transcriptome and identified the local t
 ranslatome- identifying over 800 transcripts for which local translation i
 s the dominant source of protein. In addition\, we have explored the uniqu
 e mechanisms neurons use to meet protein demands at synapses\, identifying
  surprising features of neuronal and synaptic protein synthesis.\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717 https://epfl.zoom.u
 s/j/62550191552?pwd=OFRDVzBHb0cyVG1wYkxUSFFEMUNPdz09
STATUS:CONFIRMED
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