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SUMMARY:[ U.S. CDMRP – Hearing Restoration Research Program Focused Rese
 arch Award | Research Funding ]
DTSTART;VALUE=DATE:20200714
DTSTAMP:20260414T211926Z
UID:209c371b4004683558ca1da1060ae696bcf7aa4d6c2b2a5943d463bf
CATEGORIES:Call for proposal
DESCRIPTION:Aim: Through the Congressionally Directed Medical Research Pro
 gram (CDMRP)\, the Department of Defense is announcing the Hearing Restora
 tion Research Program (HRRP) Awards. The HRRP Focused Research Award suppo
 rts promising research that will accelerate drug discovery and therapeutic
  development for hearing restoration or accelerate advances in the assessm
 ent\, diagnosis\, and treatment of auditory dysfunction. The FY20 HRRP str
 ongly encourages applicants to propose research that overcomes major obsta
 cles to hearing restoration or advances diagnosis of acute auditory system
  injury in austere or remote environments.\n\nAll applications for HRRP fu
 nding must specifically address at least one of the Focus Areas\, which ar
 e listed at the end of this announcement.\n\nThis award mechanism may be u
 sed to support preclinical studies in animals and/or clinical research inv
 olving human subjects and human anatomical substances. To support research
  projects at different stages and the exploration/development of ideas of 
 different maturity levels\, two different funding levels are available und
 er this Program Announcement:\n\n	Funding Level 1 supports exploratory\, h
 igh-risk/high-reward research that is in the earliest stages of idea devel
 opment. Research must have the potential to yield new avenues of investiga
 tion\, such as new approaches\, new research tools\, or new paradigms. Pre
 liminary data are not required.\n	Funding Level 2 supports the advancement
  of more mature research toward clinical translation. Applications may foc
 us on any phase of research from basic through translational. Applications
  proposing translational research may include a pilot clinical trial (PCT)
  component.\n\n\nFunding:        Level 1-          max. $25
 0’000\nLevel 2-           max. $1’250’000\n\nDuration:  
     Level 1-          2 years\n               
          Level 2-          3 years\n\nEligibility: Applic
 ants from international organizations or institutions are eligible to appl
 y\, and there are no citizenship restrictions. Independent investigators a
 t all academic levels (or equivalent) are eligible to serve as Principal I
 nvestigator (PI) on the application.\n\nHow to Apply: Pre-applications are
  submitted through the eBRAP platform. They should contain contact informa
 tion\, a preproposal narrative\, and a list of collaborators and key perso
 nnel as suggested on the platform. Full applications (by invitation) will 
 be made via a Grants.gov workspace. Full application packages can be downl
 oaded from Grants.gov at any time.\n\nPre-Application Deadline: 14-July-20
 20\, 5:00 p.m. EST\nFull Application Deadline: 03-November-2020\, 11:59 p.
 m. EST\n\nGrants.gov Funding Opportunity Number: W81XWH-20-HRRP-FRA\n\nFur
 ther information\n\n\n	To see the program announcement\, navigate to the s
 earch page on Grants.gov and search for the Opportunity Number W81XWH-20-H
 RRP-FRA\n	For questions about the eBRAP or Grants.gov platforms\, contact 
 the Research Office.\n\n\nFY20 Focus Areas\n\n\n	Accelerate translation of
  biological regeneration/repair mechanisms into therapies that treat audit
 ory system injury and restore auditory function.\n	Diagnostic tests that h
 elp differentiate sensory\, neural\, synaptic\, and central processing dis
 orders\, that may inform applicability and outcomes for current or future 
 hearing restoration therapeutics.\n	Develop reliable in-vitro human models
  to facilitate the understanding\, derivation\, and characterization of hu
 man auditory cells\, and/or to facilitate the evaluation of hearing restor
 ation therapies.\n	Develop and/or validate techniques/methods beyond the a
 udiogram to diagnose acute auditory system injury in austere or remote env
 ironments. For example\, but not limited to\, simple and rapid assessments
  that are compatible with portable platforms.\n
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STATUS:CONFIRMED
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