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SUMMARY:'Thiol-based Redox Signaling'
DTSTART:20201013T161500
DTSTAMP:20260404T084901Z
UID:832868a9acd1935f236768362895c62371a3aaba5839b7508cd7c29e
CATEGORIES:Conferences - Seminars
DESCRIPTION:PD Dr.  Tobias P. Dick\,\n\nGerman Cancer Research Center (
 DKFZ)\, Heidelberg. \nPD Dr. Tobias P. Dick\, at the German Cancer Rese
 arch Center (DKFZ)\, Heidelberg\, develops tools for the visualization an
 d manipulation of redox processes in vivo. He uses these tools to investig
 ate adaptive stress responses in normal and tumor cells. \n\nAbout the ta
 lk\nRedox signaling is a process by which endogenous oxidants\, derived fr
 om metabolism\, reversibly modify particular thiols on particular proteins
  to change their functional behavior in an adaptive manner. However\, the 
 molecular mechanisms of redox signaling remain largely unknown. In many ca
 ses\, specificity and efficiency of redox signaling remain unexplained. An
  emerging solution to this conundrum is that redox signaling can be mediat
 ed and channeled by protein-to-protein redox relay chains. There is growin
 g evidence that H2O2 signals are relayed through thiol peroxidases to nei
 ghboring proteins within supramolecular assemblies.\n\nAbout the speaker\n
 Tobias Dick studied Biochemistry at the Free University of Berlin and obt
 ained a PhD in Molecular Immunology working with Hans-Georg Rammensee at t
 he University of Tübingen. He was a Postdoctoral Fellow with Peter Cressw
 ell at Yale University and then continued as an independent group leader i
 n the field of Redox Biology at the German Cancer Research Center (DKFZ) i
 n Heidelberg. In 2010\, he was appointed Head of the Division of Redox Bio
 logy at DKFZ. Tobias Dick works on the molecular mechanisms of redox signa
 ling and protein redox regulation. He develops tools for the visualization
  and manipulation of redox processes in vivo. He uses these tools to inves
 tigate adaptive stress responses in normal and tumor cells.  \n\nThe talk
  will take place via Zoom (link will be sent to registered participants\, 
 a few days before the event)\nTo join this event registration is compulsor
 y! \n>> Register\nDeadline to register : October 8\, 2020
LOCATION:
STATUS:CONFIRMED
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