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SUMMARY:EPFL BioE Talks SERIES  "High-Resolution Neuroelectronic Interface
 s Enabled by Nanoscale Soft Conductors"
DTSTART:20201102T160000
DTEND:20201102T163000
DTSTAMP:20260512T041041Z
UID:2a932c5e0f76a8165bd211c1987eb467493636f3ae713cfb2b544b30
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Flavia Vitale\, University of Pennsylvania\, Philadelphi
 a\, PA (USA)\nWEEKLY EPFL BIOE TALKS SERIES\n\n(note that this talk is num
 ber one of a double-feature seminar - see details of the second talk here)
 \n\nAbstract:\nNeuroelectronic technologies are enabling paradigm-shifting
  approaches to treating neurological disorders\, restoring and repairing l
 ost functions\, and modulating neural circuitry to control mood and behavi
 or. Conventional neuroelectronic interfaces rely on metals and silicon\, w
 hich are expensive to source and process\, and are intrinsically inadequat
 e to address the mechanical\, chemical\, and electrical properties of neur
 al tissues. Thus\, the realization and successful clinical translation of 
 safe\, biocompatible\, and long-term stable neuroelectronic interfaces req
 uire significant innovations in materials and fabrication strategies. Nano
 structured carbon materials are uniquely positioned to address these chall
 enges\, as they combine remarkable electronic and electrochemical properti
 es\, with intrinsically high mass-specific surface area and mechanical fle
 xibility. Furthermore\, they can be easily integrated within scalable solu
 tion-based processing\, thus allowing easy modulation of their electronic\
 , mechanical\, and optical properties.\nIn this talk\, I will discuss how 
 nanoscale soft conductors can be engineered into high-resolution\, minimal
 ly invasive neuroelectronic interfaces designed to seamlessly map and cont
 rol the activity of neural circuits at multiple scales. Specifically\, I w
 ill describe the fundamental electrochemical properties of 2D transition m
 etal carbides (a.k.a. MXenes) for recording and stimulation characterized 
 via experimental and modeling analysis\, and how these translate into sign
 ificant impedance and noise reduction when MXenes are integrated into cell
 ular-scale devices. Then\, I will present ad hoc\, scalable\, rapid manufa
 cturing processes designed to translate the exceptional material propertie
 s at the molecular scale into high-resolution\, low impedance neuroelectro
 nic interfaces that are also compatible with clinical neuroimaging modalit
 ies\, such a magnetic resonance imaging (MRI) and computerized tomography 
 (CT).  Finally\, to illustrate the potential of MXene-based neuroelectron
 ics\, I will present different examples of applications in both implantabl
 e and wearable devices.\n\nBio:\nDr. Flavia Vitale is an Assistant Profess
 or of Neurology\, Bioengineering\, and Physical Medicine & Rehabilitation 
 at the University of Pennsylvania. She is also a core faculty member in t
 he Center for Neuroengineering and Therapeutics\, the Brain Science\, Tran
 slation\, Innovation\, and Modulation Center at Penn and of the Center of 
 Neurotrauma\, Neurodegeneration & Restoration at the Philadelphia VA Medi
 cal Center. Her research interests focus on bioelectronic materials and de
 vices for the study\, diagnosis\, and treatment of neurological and neurom
 uscular disorders.\n\n\n\nZoom link (with registration) for attending remo
 tely: https://go.epfl.ch/EPFLBioETalks\n\n\nIMPORTANT NOTICE: due to restr
 ictions resulting from the ongoing Covid-19 situation\, this seminar can b
 e followed via Zoom web-streaming only\, following prior one-time registra
 tion through the link above.
LOCATION:via Zoom web-streaming only\, due to Covid-19 situation https://g
 o.epfl.ch/EPFLBioETalks https://go.epfl.ch/EPFLBioETalks
STATUS:CONFIRMED
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