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SUMMARY:Shedding Light on Tumour Evolution
DTSTART:20201127T170000
DTEND:20201127T180000
DTSTAMP:20260407T042153Z
UID:3f68d61a16914310cb91bf91abfdca80830da493929959e901cac841
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Sarah Bohndiek\, University of Cambridge \nThis event i
 s part of the EPFL Seminar Series in Imaging (https://imagingseminars.org)
 .\n\nAbstract. The dynamic cellular ecosystem of a growing tumour mass req
 uires a vascular network to obtain oxygen and nutrients\, as well as to 
 remove metabolic waste products. Early in their development\, tumours st
 imulate new blood vessel growth through a range of mechanisms to meet th
 is need\, leading to marked differences in the vasculature between normal
  and tumour tissue that could be exploited for early cancer detection an
 d monitoring of therapy response. These differences in vascular phenotype
 s can be revealed using optics\, thanks to the strong absorption of ligh
 t by oxy- and deoxy-haemoglobin.\n\nIn this talk\, I will introduce our ef
 forts to harness next-generation imaging sciences to visualise tumour arch
 itecture and function non-invasively. In particular\, I will introduce pho
 toacoustic imaging and explain how its multiscale implementations can prov
 ide insight into vascular evolution and remodelling in response to treatme
 nt in animal models. I will then provide an overview of the future clinica
 l challenges and opportunities in using photoacoustic imaging in patients.
 \n\nBiography. Prof. Sarah Bohndiek is Group Leader at the University of C
 ambridge\, where she is jointly appointed in the Department of Physics and
  the Cancer Research UK Cambridge Institute. The broad mission of Sarah’
 s interdisciplinary team\, the VISIONLab\, is advance our understanding of
  tumour evolution using next-generation imaging sciences. They are also ar
 e active in translating their findings into clinical trials. Sarah was re
 cently awarded the CRUK Future Leaders in Cancer Research Prize and SPIE E
 arly Career Achievement Award in recognition of her interdisciplinary rese
 arch innovation.
LOCATION:https://epfl.zoom.us/j/84411936844
STATUS:CONFIRMED
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