BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Memento EPFL// BEGIN:VEVENT SUMMARY:Functional Ultrasound Imaging: a New Neuroimaging Modality for Neu roscience DTSTART:20201120T170000 DTEND:20201120T180000 DTSTAMP:20260921T101717Z UID:d023296024d79814f2c5f1943b7625cc48a363c1f5d4f1c238609603 CATEGORIES:Conferences - Seminars DESCRIPTION:Prof. Mickael Tanter\, INSERM\, ESPCI Paris\nThis event is pa rt of the EPFL Seminar Series in Imaging (https://imagingseminars.org).\n\ nAbstract. In the last twenty years\, the progressive introduction of plan e or diverging ultrasonic wave transmissions rather than line by line scan ning focused beams broke the resolution limits of ultrasound imaging. By u sing such large field of view transmissions\, the frame rate reaches the t heoretical limit of physics dictated by the ultrasound speed and an ultras onic map can be provided typically in tens of micro-seconds (several thous ands of frames per second). Interestingly\, this leap in frame rate is not only a technological breakthrough but it permits the advent of completely new ultrasound imaging modes\, including shear wave elastography\, electr omechanical wave imaging\, ultrafast Doppler\, ultrafast contrast imaging\ , and even functional ultrasound imaging (fUS imaging) of brain activity i ntroducing Ultrasound as an emerging full-fledged neuroimaging modality.\n \nAt ultrafast frame rates\, it becomes possible to track in real time the transient vibrations – known as shear waves – propagating through org ans. Such "human body seismology" provides quantitative maps of local tiss ue stiffness whose added value for diagnosis has been recently demonstrate d in many fields of radiology (breast\, prostate and liver cancer\, cardio vascular imaging\, ...).\n\nFor blood flow imaging\, ultrafast Doppler per mits high-precision characterization of complex vascular and cardiac flows . It also gives ultrasound the ability to detect very subtle blood flow in very small vessels. In the brain\, such ultrasensitive Doppler paves the way for fUltrasound or fUS (functional ultrasound) imaging of brain activi ty with unprecedented spatial and temporal resolution compared to fMRI. It provides the first modality for imaging of the whole brain activity worki ng on awake and freely moving animals with unprecedented resolutions and w as also translated recently to clinics.  \n\nFinally\, we recently demons trated that it can be combined with 3 µm diameter microbubbles injections in order to provide a first in vivo and non-invasive imaging modality at microscopic scales deep into organs combined with contrast agents by local izing the position of millions of microbubbles at ultrafast frame rates.\n \nThis ultrasound localization microscopy technique solves for the first t ime the problem of in vivo imaging at microscopic scale the whole brain va sculature. Beyond fundamental neuroscience or stroke diagnosis\, it will c ertainly provide new insights in the understanding of tumor angiogenesis\, for example combined with PET/CT imaging.\n\nBiography. Mickael Tanter is a research professor of the French National Institute for Health and Medi cal Research (Inserm)\, distinguished professor of ESPCI Paris and AXA Cha ir Professor. He is heading the laboratory Inserm “Physics for Medicine Paris” (Inserm\, CNRS\, ESPCI Paris)\, Paris\, France. He is also the di rector of the first Inserm Technology Research Accelerator created in 2016 and dedicated to Biomedical Ultrasound. Mickael Tanter is a world-renowne d expert in biomedical ultrasound and wave physics. He authored more than 350 peer-reviewed papers and book chapters and is the recipient of 50 inte rnational patent families. In the last 20 years\, he co-invented several m ajor innovations in Biomedical Ultrasound: Transient Elastography\, Ultraf ast Ultrasound and Shear Wave Elastography\, functional Ultrasound (fUS) i maging of brain activity and Superresolution Ultrasound based on Ultrasoun d Localization Microscopy. He received many national and international dis tinctions (among them the Honored Lecture of the Radiology Society of Nort h America in 2012\, the Grand Prize of Medicine and Medical Research of Pa ris city in 2011\, the Grand Prize of Fondation de la Recherche Médicale in 2016 and the Carl Hellmuth Hertz Prize of IEEE Ultrasonics\, Ferroelect rics and Frequency Control society in 2017\, and the highest distinction o f the European Society in Molecular Imaging ESMI in 2018). M. Tanter is al so the co-founder of several MedTech companies in Biomedical Ultrasound (S upersonic Imagine\, CardiaWave\, Iconeus) and is elected member of the Eur opean Academy of Science. LOCATION:https://epfl.zoom.us/j/86245626220 STATUS:CONFIRMED END:VEVENT END:VCALENDAR