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SUMMARY:Talk by Christof Koch - ‘Modeling the Human Brain – A Long-Ter
 m Perspective’
DTSTART:20210119T170000
DTEND:20210119T180000
DTSTAMP:20260427T203417Z
UID:3c46f8d6e906d5b4574173b80f4bc1a2eb9f108c22c4acc8d1dbc487
CATEGORIES:Conferences - Seminars
DESCRIPTION:Christof Koch\nBlue Brain is delighted to welcome Christof Koc
 h\, Chief Scientist\, MindScope Program\, Allen Institute\, Seattle\, US
  for his virtual talk on ‘Modeling the Human Brain – A Long-Term Per
 spective’.\n\nAbstract: \n\nThe best understood cortex is primary visua
 l cortex of the mouse. This is witnessed by state-of-the-art simulation of
  ~1 mm3 of V1 from the adult mouse\, using two different levels of granula
 rity (point neurons\, spatially extended HH models). These models\, based 
 on the massive Allen Institute databanks functional connectivity and in vi
 vo recordings\, replicate in vivo spiking data the model was not trained o
 n in a quantitative manner (Billeh et al.\, Neuron 2020). It is being exte
 nded to include detailed connectivity of electron-microscopically reconstr
 ucted data from mouse V1. It is likely that within a few decades such mode
 ls could be extended to faithfully simulate the brain and the behavior of 
 mice\, predicting genuine new phenomena and system-level properties. \n\n
 The human brain is three orders of magnitude bigger than the mouse brain. 
 There is currently little evidence to suggest that it is\, per unit volume
 \, significantly more complex than the mouse brain. The field is now in th
 e first stages of assembling a dataset of individual human pyramidal neuro
 ns and interneurons\, based on in vitro data from neurosurgical samples. T
 his provides a first\, but limited view\, onto the human brain circuits at
  the cellular level. For the foreseeable future\, we will not have access 
 to in vivo cellular data nor synaptic learning rules. This will impose uni
 que limits onto our ability to faithfully simulate the human brain at the 
 micro-functional level over the thirty or more years. \n\nShort bio: \n\
 nChristof Koch\, PhD is a neuroscientist best known for his studies and wr
 itings exploring the brain basis of consciousness. Trained as a physicist\
 , Koch was for 27 years a professor of biology and engineering at the Cali
 fornia Institute of Technology in Pasadena before moving to the Allen Inst
 itute in Seattle\, where he became the Chief Scientist and then the Presid
 ent in 2015. He is now the Chief Scientist of the MindScope Program at the
  Allen Institute\, using the Neuropixels and Mesoscope Brain Observatories
  to track and analyze the dynamics of tens of thousands of cortical neuron
 s and their linkage to visuo-motor behavior and visual perception in mice.
  \n\nDr. Koch is interested in the biophysics and neurophysiology of cort
 ical tissue\, brain-machine interfaces\, conscious experiences and what th
 ey imply about the mind and the brain. He published his first paper on the
  neural correlates of consciousness with the molecular biologist Francis C
 rick more than thirty years ago.\n\nDr. Koch is a vegetarian who lives in 
 the Pacific North-West\, loves big dogs\, biking\, running\, climbing and 
 rowing. His latest book is The Feeling of Life Itself – Why Consciousnes
 s is Widespread but Can’t be Computed.\n\nFor more information\, see ww
 w.christofkoch.com\n\n\n 
LOCATION:Zoom meeting https://epfl.zoom.us/meeting/register/tZEqduCorDIoH9
 ZgJ38kYSb-QRNkMwQ3vLcn
STATUS:CONFIRMED
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