BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Memento EPFL// BEGIN:VEVENT SUMMARY:IMX Seminar Series - Life on nano: engineering surfaces of colloid al nanoparticles for life science applications DTSTART:20210419T131500 DTEND:20210419T141500 DTSTAMP:20260405T203031Z UID:0fb5461184e1e3fb3a4183101073113b056f84e578b7ab84b8dbd589 CATEGORIES:Conferences - Seminars DESCRIPTION:Prof. Lucia Curri\, University of Bari\, Italy\nIn the last ye ars\, the extraordinary advances in the field of nanomaterial science have resulted in a great potential for applications in life science. A variety of preparative and post-preparative colloidal routes have demonstrated th e ability to access a wide choice of inorganic nanoparticles (NPs) and nan ocrystals (NCs)\, with different compositions\, that can be achieved with a high control on size\, shape and surface chemistry\, ultimately tailorin g their electronic\, optical\, magnetic\, thermal and chemical size depend ent properties.\nA range of functionalization strategies have been develop ed to suitably engineer the surface of NPs and NCs and tune their specific chemical reactivity towards the surrounding environment. The control of n ano-bio interfaces has demonstrated to be essential to enable nanomaterial s conjugation and combination with biologically relevant entities\, thus p roducing advanced materials for diagnosis and therapy.\nThe ability of eng ineering the surface of specialized nanomaterials\, such as semiconductors \, plasmonic and magnetic nanostructures\, with tailored procedures\, allo wing to ingeniously combine NPs and NCs with peptides\, drugs and other si gnificant biological systems\, is decisive for their application in diagno sis and treatment of different diseases\, including cancer and neurodegene rative disorders. Examples of drug delivery\, labelling\, diagnostic and t heranostics systems\, based on the combination of NIR photoactive nanomate rials\, plasmonic nanostructures and magnetic NPs with relevant biological functions will be illustrated.\nReferences\n- G. Siciliano et al “Gold ‐speckled SPION@SiO2 nanoparticles decorated with thiocarbohydrates for ASGPR1 targeting: towards HCC dual mode imaging potential applications” (2020) Chemistry–A European Journal 26 (48)\, 11048-11059.\n- De Angelis et al “Stimuli-responsive nanoparticle-assisted immunotherapy: a new we apon against solid tumours”(2020) J. Mater. Chem. B 8 (9)\, 1823-1840.\n - C. Ingrosso et al “Au nanoparticle in situ decorated RGO nanocomposite s for highly sensitive electrochemical genosensors” (2019) J. Mater. Che m. B.\, 7\, 768-777.\n- C. Ingrosso et al “Ascorbic acid-sensitized Au n anorods-functionalized nanostructured TiO2 transparent electrodes for phot oelectrochemical genosensing” (2018) Electrochimica Acta 276\, 389-398.\ n- N. Depalo et al “NIR emitting nanoprobes based on cyclic RGD motif co njugated PbS quantum dots for integrin-targeted optical bioimaging” (201 7) ACS Applied Materials and Interfaces\, 9 (49)\, 43113–43126.\n- G. Va lente\, et al “Integrin-targeting with peptide-bioconjugated semiconduct or-magnetic nanocrystalline heterostructures“ (2016) Nano Research\, 9\, 644-662.\n- E. Fanizza et al ”Highly selective luminescent nanostructur es for mitochondrial imaging and targeting” (2016) Nanoscale\, 6\, 3350- 3361\nBio: Lucia Curri received her PhD from the University of Bari (Italy ) in 1997\, between 1995 and 1996 was Research Assistant at Chemistry Depa rtment of University College London (UK)\, then in 1997 she started workin g at CNR\, first as research scientist and since 2010 as senior research s cientist. In October 2018 she has been appointed full professor of Physica l Chemistry at Chemistry Department of University of Bari Aldo Moro.\nShe has contributed to advance the knowledge in the field of materials science \, developing original strategies for the preparation and functionalizatio n of colloidal nanocrystals based inorganic and hybrid materials\, both fo r fundamental and application studies.\nShe has built a solid and recogniz ed expertise in surface engineering of nanoparticles and nanocrystals\, in order to achieve bioconjugation\, organization into mesoscale structures (films\, 2/3 D assemblies) with tailored functional collective properties and integration in nanocomposites for their micro/nano fabrication by mean s of conventional and innovative techniques.\nIn particular\, she has stro ngly contributed to apply the potential of such nanomaterials in environme ntal technologies\, including detection and degradation of pollutants for water and air purification. More recently her interests have expanded to b iomedical field\, focusing on the research on original theranostic nanosys tems for diagnosis and therapy of different diseases.\nShe has been and is research unit PI in several National and International (European FP6\, FP 7\, and H2020) research projects in the field of synthesis\, functionaliza tion and applications of colloidal nanoparticles\, and has coordinated the European Project 7th FP LIMPID "Nanocomposite Materials for Photocatalyti c Degradation of Pollutants" (G.A. 310177).\nLucia Curri has been member o f Panel PE5 for ERC Consolidator grant (2016-2018)\, chairing the same Pan el in 2020 and has participated to several Conference Committees and Board s\, and has been expert evaluator for European Commission (FP7 and H2020 p rojects) and various other International funding agencies.\nShe is lecture r in master\, doctoral and post-doctoral courses at University of Bari and in several national and international schools and is supervisor for degre e and doctoral projects at the Department of Chemistry University of Bari – Bari (Italy). She has been supervisor of several CNR fellowship recipi ent\, CNR research assistants and research fellows.\nShe is member of the Chemical Science Doctoral Board at University of Bari and of evaluation co mmittees for national and international PhD theses.\nShe is co-author of o ver 210 ISI papers\, including more than 185 articles on JCR peer-reviewed journals and many other publications such as 10 chapters in books and sev eral conference proceedings in national and nternational conferences\, als o as invited speaker ( (H index= 41 source Scopus\, H index= 40 source WoS \, H index 43 source Google Scholar - Apr 2021). LOCATION:https://epfl.zoom.us/j/95940364570 STATUS:CONFIRMED END:VEVENT END:VCALENDAR