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SUMMARY:EPFL BioE Talks SERIES  "MiNDS: Miniaturized Neural Drug Delivery 
 System - A Flexible Shuttle to the Brain"
DTSTART:20210322T160000
DTEND:20210322T163000
DTSTAMP:20260510T165010Z
UID:d2e39a0c4a9d94137611a0e9b592a1ad36bb5146f79e8d1284579664
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Canan Dağdeviren\, MIT Media Lab\, Massachusetts Instit
 ute of Technology\, Cambridge\, MA (USA)\nWEEKLY EPFL BIOE TALKS SERIES\n
  \n(note that this talk is number one of a double-feature seminar - see d
 etails of the second talk here)\n\nAbstract:\nDespite some improvements in
  understanding the pathophysiological effects related to neurodegenerative
  disorders\, there is a deficit of suitable technologies that can keep up 
 with the rapid dynamics of neural circuits—a requirement for more effect
 ive treatments. For example\, conventional drugs are administered orally o
 r intravenously\, leading to drug distribution throughout the body. This r
 esults in delivery kinetics with disadvantages of (i) systemic toxicity\, 
 (ii) escalating dosing regimens\, and (iii) limited therapeutic efficacy. 
 This is why the ability to modulate neural pathways directly inside the br
 ain is crucial. Our recent work overcomes these issues and leads an emergi
 ng field that performs targeted delivery of chemicals for effective neurom
 odulation. We achieved this by microfabricating a miniaturized neural drug
  delivery system\, called MiNDS\, that modulates neural functions and rela
 ted behavior in animal subjects\, with cell-type specificity and high spat
 ial and temporal precision\, while simultaneously recording neuronal elect
 roencephalographic (EEG) activity to enable feedback control. Microfabrica
 tion allows customizable and mechanically robust devices with various leng
 ths and diameters to accommodate both small and large animals\, without re
 quiring a guide tube for implantation. The versatile functionality of this
  biocompatible\, miniaturized device platform (<200 μm in diameter) permi
 ts local\, on-demand chemical neuromodulation.\n\nBio:\nCanan Dagdeviren i
 s the LG Career Development Professor of Media Arts and Sciences at MIT Me
 dia Lab\, where she leads the Conformable Decoders research group since Ja
 nuary 2017. The group aims to convert the patterns of nature and the human
  body into beneficial signals and energy.\nDagdeviren earned her Ph.D. in 
 Materials Science and Engineering from the University of Illinois at Urban
 a-Champaign\, where she focused on exploring patterning techniques and cre
 ating piezoelectric based biomedical systems. As a Junior Fellow of the So
 ciety of Fellows at Harvard University\, Dr. Dagdeviren conducted her post
 doctoral research at the MIT David H. Koch Institute for Integrative Cance
 r Research.\n\nDagdeviren’s work has been featured in many media outlets
 \, including TIME\, Washington Post\, Smithsonian Magazine\, Popular Mecha
 nics\, CBS News\, BBC News and Physics World. In 2015\, MIT Technology Rev
 iew named her among the "Top 35 Innovators Under 35" and Forbes selected h
 er as one of the "Top 30 Under 30 in Science". Recently\, Dagdeviren has b
 een named as a Spotlight Health Scholar by Aspen Institute and World #1 in
  Medical Innovation Category of Ten Outstanding Young Persons of the World
  (TOYP) by Junior Chamber International. In 2016\, Dr. Dagdeviren was awar
 ded the Science & Sci Life Prize for Young Scientists in Translational Med
 icine Category and invited to attend Nobel Prize Ceremony in Stockholm\, S
 weden. Recently\, Dr. Dagdeviren has been named as 2017 Innovation and Tec
 hnology Delegate by the American Academy of Achievement. In 2019 Dr. Dagde
 viren was among 87 of the nation’s brightest young engineers who have be
 en selected to take part in the National Academy of Engineering’s (NAE) 
 25th annual U.S. Frontiers of Engineering (USFOE) symposium\, hosted by Bo
 eing in Charleston\, South Carolina.\n\n\n\nZoom link (with registration) 
 for attending remotely: https://go.epfl.ch/EPFLBioETalks\n\n\nIMPORTANT NO
 TICE: due to restrictions resulting from the ongoing Covid-19 pandemic\, t
 his seminar can be followed via Zoom web-streaming only\, (following prior
  one-time registration through the link above).
LOCATION:via Zoom web-streaming only\, due to Covid-19 pandemic https://go
 .epfl.ch/EPFLBioETalks https://go.epfl.ch/EPFLBioETalks
STATUS:CONFIRMED
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