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BEGIN:VEVENT
SUMMARY:EPFL BioE Talks SERIES  "How Human Cells Deal With Genome Editing 
 Tools"
DTSTART:20210503T160000
DTEND:20210503T170000
DTSTAMP:20260506T040439Z
UID:011df80855a7e996cd1ab2652abadc011d928e105624f6d2c4044e6e
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Jacob Corn\, ETH Zurich (CH)\nWEEKLY EPFL BIOE TALKS SER
 IES\n\nAbstract:\nGenome manipulation with CRISPR-Cas systems has rapidly 
 expanded in scope to include a dizzying array of Cas enzymes and engineere
 d tools. The success of these systems completely depends upon cellular pat
 hways that turn Cas-targeted insults into desired genomic outcomes. Our su
 rprisingly poor understanding of the mechanisms underlying genome editing 
 necessitates extensive trial-and-error\, generally starting from scratch i
 n each new cellular and organismal context. The Corn lab studies how cells
  deal with genome editing tools\, with an eye towards hypothesis-driven de
 sign of personalized therapies.\n\nBio:\nJacob Corn is the Professor of Ge
 nome Biology at the ETH Zurich. His research aims to better understand and
  treat disease through next-generation genome editing technologies. Jacob
 ’s career has bridged academia and industry\, working in therapeutic are
 as that include infectious disease\, neurobiology\, and oncology. His rese
 arch takes a multidisciplinary approach\, combining cellular biochemistry\
 , functional genomics\, computational biology\, bioengineering\, and bioph
 ysics. Jacob’s graduate studies at the University of California\, Berkel
 ey with James Berger explored how cells replicate their genomes\, and was 
 recognized with several honors\, including the Nicholas Cozzarelli and Har
 old Weintraub awards. Jacob’s work as a Jane Coffin Childs postdoctoral 
 fellow at the University of Washington created the world’s first computa
 tionally designed de novo protein interaction and a protein-based inhibito
 r to treat flu. Jacob began his independent research career as a group lea
 der at Genentech\, where his lab discovered biological mechanisms for chal
 lenging therapeutic targets. Jacob then moved back to academia as the foun
 ding Scientific Director of the Innovative Genomics Institute and faculty 
 at UC Berkeley. His lab’s current focus is the development of genome ed
 iting\, the mechanisms by which cells repair their DNA\, and the maintenan
 ce of healthy organelles. In his spare time\, Jacob enjoys trips in the mo
 untains and rock climbing.\n\n\nZoom link (with registration) for attendin
 g remotely: https://go.epfl.ch/EPFLBioETalks\n\n\nIMPORTANT NOTICE: due to
  restrictions resulting from the ongoing Covid-19 pandemic\, this seminar 
 can be followed via Zoom web-streaming only\, (following prior one-time re
 gistration through the link above).
LOCATION:via Zoom web-streaming only\, due to Covid-19 pandemic https://go
 .epfl.ch/EPFLBioETalks https://go.epfl.ch/EPFLBioETalks
STATUS:CONFIRMED
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