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SUMMARY:Shaping fluid lipid membranes with proteins and cytoskeletal filam
 ents
DTSTART:20210503T161500
DTEND:20210503T171500
DTSTAMP:20260406T063959Z
UID:24c2e9b013113258877a5291b4c57ea7b2adb392ecc5e04800907e58
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Patricia Bassereau\, Institut Curie\, Laboratoire Physic
 o Chimie Curie\, Paris\n§Cell membranes are highly deformable and have to
  be strongly curved\, for instance during trafficking when small buds form
  and eventually detach from cell membranes\, or during cell migration upon
  the formation of actin-sustained cellular protrusions (filopodia). These 
 membrane-shaping processes always require the interaction with proteins (f
 or instance\, BAR domain proteins with an intrinsically-curved shape) and 
 in some cases with the actin cytoskeleton. In vitro membrane systems with 
 controlled curvature combined to theoretical models have been instrumental
  for understanding how proteins and cytoskeleton shape cellular membranes\
 , and conversely how membrane curvature is a cue for the local enrichment 
 of peripheral or integral proteins with non-symmetric shape. Similarly\, t
 hey help understanding how non-curvature sensing proteins are recruited on
  curved membranes. In this talk\, I will discuss examples of proteins with
  intrinsically-curved shapes that are enriched in curved membranes\, how t
 hey assist the recruitment of non-curvature sensing proteins\, or induce f
 ilopodia generation\, due to their intrinsic coupling to membrane curvatur
 e.
LOCATION:https://epfl.zoom.us/j/82443983203
STATUS:CONFIRMED
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