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SUMMARY:Human Organs on Chips and Programmable Nanotherapeutics at the Wys
 s Institute
DTSTART:20120919T111500
DTSTAMP:20260413T111143Z
UID:bb79e50eb8184e08375f9fc7afd58cc9a52f48bb4533e4a3f8e19310
CATEGORIES:Conferences - Seminars
DESCRIPTION:Donald E. Ingber\, MD\, PhD\, Harvard University\nIn this pres
 entation\, I will describe work we have been carrying out in the Programma
 ble Nanomaterials and Biomimetic Microsystems platforms at the Wyss Instit
 ute for Biologically Inspired Engineering at Harvard\, as well as our new 
 model for innovation\, collaboration and technology translation.  The goa
 l of the first platform is to create multi-functional nanotechnologies for
  regenerative medicine and drug delivery applications\, with the long-term
  goal of developing injectable programmable devices for biomedicine. The s
 econd seeks to engineer microchips lined by living human cells that recapi
 tulate organ-level functions as a way to replace animal testing for drug d
 evelopment.  In this presentation\, I will review recent advances we have
  made on development of human lung\, gut and bone marrow chips and describ
 e two new bioinspired nanotechnologies.  The first is a Fluid Shear-Activ
 ated Drug Delivery System for injection of therapeutics that one desires t
 o target to embolic or stenotic vascular lesions. The second relates to a 
 new methodology for producing programmable nanotherapeutic devices using D
 NA origami as a manufacturing system.
LOCATION:SV1717a
STATUS:CONFIRMED
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