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SUMMARY:Biomimetic Natural Product Synthesis
DTSTART:20211123T171500
DTEND:20211123T181500
DTSTAMP:20260527T162820Z
UID:b103da7b9bca10180f5329ae28ad74b33cffa37cb797bc8c9e519bdb
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Andrew Lawrence\, University of Edinburgh\, UK http://ww
 w.chem.ed.ac.uk/staff/academic-staff/professor-andrew-l-lawrence\nAbstract
 : This presentation will be an account of our research into how molecular 
 complexity is rapidly and selectively generated in biosynthetic pathways. 
 We are focused on developing step-economical total syntheses that facilita
 te the production of practical quantities of our target molecules. This ap
 proach towards total synthesis enables greater collaborative research on t
 he properties of these natural products whilst forcing us to tackle import
 ant reactivity and selectivity issues without resorting to the excessive u
 se of non-strategic manipulations. By following a biomimetic approach we h
 ave developed several bio-inspired domino reaction sequences that rapidly 
 and selectively generate molecular complexity (i.e.\, new bonds\, rings an
 d stereogenic elements). We are simultaneously\, therefore\, able to impro
 ve synthetic organic chemistry whilst probing fundamental questions regard
 ing the chemistry of biosynthetic pathways.\n 
LOCATION:AUDITOIRE CE1
STATUS:CONFIRMED
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