Event List
retrieve:
Return the details about the given Event id.
list:
List all Event objects.
GET /api/v1/events/?format=api&offset=110&ordering=-event__contact
{ "count": 266, "next": "https://memento.epfl.ch/api/v1/events/?format=api&limit=10&offset=120&ordering=-event__contact", "previous": "https://memento.epfl.ch/api/v1/events/?format=api&limit=10&offset=100&ordering=-event__contact", "results": [ { "id": 72342, "title": "Dynamics in Brain-inspired Neural Networks // 2-6 November 2026", "slug": "dynamics-in-brain-inspired-neural-networks-2-6-nov", "event_url": "https://memento.epfl.ch/event/dynamics-in-brain-inspired-neural-networks-2-6-nov", "visual_url": null, "visual_large_url": null, "visual_maxsize_url": null, "lang": "en", "start_date": "2026-11-02", "end_date": "2026-11-06", "start_time": "13:30:00", "end_time": "12:00:00", "description": "<p>The brain forms a large recurrent spiking neural network with extremely high connectivity making time-dependent mean-field approaches valuable tools to translate the microscopic level of single-neuron dynamics to the mesoscopic or macroscopic level. In recent years, experimental data as well as simulation studies have highlighted the importance of low-dimensional macroscopic dynamics in large recurrent spiking networks. On the theory side, the notion of low-rank connectivity has shifted into the focus of interest. <br>\r\nThis meeting will to bring together researchers in mathematical and theoretical neuroscience who address the above topics from different perspectives. <br>\r\n<br>\r\n<strong>Phase 1</strong><br>\r\nPublic lectures from Monday afternoon – Wednesday end of day<br>\r\n<br>\r\nPresentations will alternate between speakers with a physics and those with a math background so as to foster links between the two communities.<br>\r\n<br>\r\n<strong>Phase 2</strong><br>\r\nTutorials for PhD students on Thursday and Friday. </p>", "image_description": "", "creation_date": "2026-08-14T10:16:34", "last_modification_date": "2026-08-14T10:20:36", "link_label": "Event website", "link_url": "https://www.epfl.ch/labs/lcn/dynamics-in-brain-inspired-neural-networks-2-6-november-2026/", "canceled": "False", "cancel_reason": "", "place_and_room": "", "url_place_and_room": "", "url_online_room": "", "spoken_languages": [], "speaker": "", "organizer": "", "contact": "[email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 1, "fr_label": "Sur inscription", "en_label": "Registration required" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121429/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/43/?format=api", "https://memento.epfl.ch/api/v1/mementos/260/?format=api" ] }, { "id": 72598, "title": "Pressure Points: Risk - Sonia Seneviratne / RIOT, MAS UTD", "slug": "pressure-points-risk-sonia-seneviratne-riot-mas-ut", "event_url": "https://memento.epfl.ch/event/pressure-points-risk-sonia-seneviratne-riot-mas-ut", "visual_url": "https://memento.epfl.ch/image/33842/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33842/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33842/max-size.jpg", "lang": "en", "start_date": "2026-10-26", "end_date": "2026-10-26", "start_time": "17:00:00", "end_time": "19:00:00", "description": "<p>“To emphasize (...) dubious uses of risk is perverse, a dirty way of talking about a<br>\r\nclean scientific subject”<br>\r\nMary Douglas, <em>Risk and Blame,</em> 36.<br>\r\n<br>\r\nAs the baseline condition of so many territories shaped by extractive industries, administrative delay, and climatic instability, risk is prevalent. Yet ecological risk—pollution, fires, floods, heatwaves, droughts—is still presented as problems to be solved rather than conditions to be inhabited. This also speaks to an outsourcing of risk through externalized consequences of spatial injustice. Banks, developers, material supply chains, normative institutions, subcontracting hierarchies —all contend with calculated risk. This edition of <u>Pressure Points</u> asks us to unpack what it means to live with the risk, how it is managed, commodified, quantified, invented, politicized, instrumentalized, tamed, and to think, design, cohabitate intellectually and physically with it. The assembled guests should help us think and build literacy toward developing tools for living within uncertain territories and futures. <br>\r\n<br>\r\n<u>Sonia Seneviratne</u><br>\r\nMonday, October 26, 17:00 CET<br>\r\n<br>\r\n<a href=\"https://usys.ethz.ch/en/people/profile.seneviratne.html\"><u>Sonia Seneviratne</u></a> is a Full Professor in Land-Climate Dynamics at ETH Zurich, with a focus on climate science and environmental physics. She conducts research on climate extremes such as droughts, land-climate processes, and human-induced climate change, based on climate modelling and data analyses. Listed among the Highly Cited Researchers of Web of Science (Clarivate) since 2014, she was a Coordinating Lead Author and Lead Author on several reports of the Intergovernmental Panel on Climate Change (IPCC), including the Special Report on Extreme Events, the Special Report on Global Warming of 1.5°C, and the Sixth Assessment Report in 2021. Seneviratne has received the Macelwane Medal of the American Geophysical Union in 2013 and the Hans-Oeschger Medal of the European Geosciences Union. Since July 2023, she serves as IPCC Working Group I Vice-Chair for the seventh assessment cycle (2023–2030). Her most recent contribution, published in June 2026, is the release of MESMER v1.0.0, an open-source climate model emulator she helped develop as part of her research group. It reproduces the spatial climate patterns of complex Earth System Models, including temperature and several climate-extreme indicators, making detailed climate information accessible to the wider research community.<br>\r\n<br>\r\n<a href=\"https://www.riot.today/\">RIOT (Research and Innovation on Territory)</a> is a laboratory engaged in pedagogy and research within the Institute of Architecture (ENAC) at the Swiss Federal Institute of Technology–EPFL, led by Charlotte Malterre-Barthes with Elif Erez, Flore Guichot, Jeremy Ratib, Summer Islam, Antoine Iweins, Kathy Kao, Nathalie Marj, Romain Dubetier-Grenier, Sylvie Clavel, and Saira Mohammed. Believing that the construction sector and design disciplines must pivot and wholeheartedly engage in the current social and climatic urgencies by rewiring themselves to face and repair the harm, RIOT utilizes tactics and strategies to decarbonize, decolonize, and depatriarchalize space production–by design. <br>\r\n<br>\r\n </p>", "image_description": "Event poster", "creation_date": "2026-09-16T14:49:25", "last_modification_date": "2026-09-25T13:42:32", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "Foyer SG", "url_place_and_room": "", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "<a href=\"https://usys.ethz.ch/en/people/profile.seneviratne.html\"><u>Sonia Seneviratne</u></a> is a Full Professor in Land-Climate Dynamics at ETH Zurich, with a focus on climate science and environmental physics. She conducts research on climate extremes such as droughts, land-climate processes, and human-induced climate change, based on climate modelling and data analyses. Listed among the Highly Cited Researchers of Web of Science (Clarivate) since 2014, she was a Coordinating Lead Author and Lead Author on several reports of the Intergovernmental Panel on Climate Change (IPCC), including the Special Report on Extreme Events, the Special Report on Global Warming of 1.5°C, and the Sixth Assessment Report in 2021. Seneviratne has received the Macelwane Medal of the American Geophysical Union in 2013 and the Hans-Oeschger Medal of the European Geosciences Union. Since July 2023, she serves as IPCC Working Group I Vice-Chair for the seventh assessment cycle (2023–2030). Her most recent contribution, published in June 2026, is the release of MESMER v1.0.0, an open-source climate model emulator she helped develop as part of her research group. It reproduces the spatial climate patterns of complex Earth System Models, including temperature and several climate-extreme indicators, making detailed climate information accessible to the wider research community.", "organizer": "RIOT, MAS UTD", "contact": "Elif Erez, [email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "risk, territory, ecology, architecture, spatial justice, material supply chains, extraction", "file": "https://memento.epfl.ch/public/upload/files/2026PressurePointsPosterA3UPDATED_6ceJTqi.jpg", "icalendar_url": "https://memento.epfl.ch/event/export/121825/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/4/?format=api", "https://memento.epfl.ch/api/v1/mementos/32/?format=api" ] }, { "id": 72599, "title": "Pressure Points: Risk - Liam Ross / RIOT, MAS UTD", "slug": "pressure-points-risk-liam-ross-riot-mas-utd", "event_url": "https://memento.epfl.ch/event/pressure-points-risk-liam-ross-riot-mas-utd", "visual_url": "https://memento.epfl.ch/image/33843/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33843/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33843/max-size.jpg", "lang": "en", "start_date": "2026-11-03", "end_date": "2026-11-03", "start_time": "17:00:00", "end_time": "19:00:00", "description": "<p>“To emphasize (...) dubious uses of risk is perverse, a dirty way of talking about a<br>\r\nclean scientific subject”<br>\r\nMary Douglas, <em>Risk and Blame,</em> 36.<br>\r\n<br>\r\nAs the baseline condition of so many territories shaped by extractive industries, administrative delay, and climatic instability, risk is prevalent. Yet ecological risk—pollution, fires, floods, heatwaves, droughts—is still presented as problems to be solved rather than conditions to be inhabited. This also speaks to an outsourcing of risk through externalized consequences of spatial injustice. Banks, developers, material supply chains, normative institutions, subcontracting hierarchies —all contend with calculated risk. This edition of <u>Pressure Points</u> asks us to unpack what it means to live with the risk, how it is managed, commodified, quantified, invented, politicized, instrumentalized, tamed, and to think, design, cohabitate intellectually and physically with it. The assembled guests should help us think and build literacy toward developing tools for living within uncertain territories and futures. <br>\r\n<br>\r\n<u>Liam Ross </u><br>\r\nTuesday, November 3, 17:00 CET<br>\r\n<br>\r\n<a href=\"https://www.eca.ed.ac.uk/profile/dr-liam-ross\"><u>Liam Ross</u></a> is an architect and senior lecturer in Architectural Design at the University of Edinburgh, with a focus on building standardisation as a mode of architectural design, and in particular on fire-safety regulation. He also examines how those standards produce surprising side-effects as they are reinterpreted in practice. His book Pyrotechnic Cities: Architecture, Fire-Safety and Standardisation was published by Routledge in 2022, and describes the way that architectural design is an instrument of political agency. <br>\r\nHis work has been exhibited and published widely, including in Architectural Research Quarterly (arq), Arch+, and journalistic outlets such as Blueprint, Prospect, and Volume.<br>\r\nRoss has experience of practice in the UK and US, including a period of 5 years with Malcolm Fraser Architects, and maintains a relationship with professional practice as co-founder of ESALA Projects, a consultancy offering pro-bono and for-fee design services to public and third-sector clients. His most recent work, published in January 2026 in Architectural Research Quarterly, includes a co-authored article with Jon Goodbun entitled ‘Design and the extended building site: Ecologies of production and the production of ecologies’, which reframes the building site as an 'extended' socioecological system reaching across the global supply chains, material extraction, and labour that construction depends on, arguing that building is an ecological and political process rather than a purely material one.<br>\r\n<br>\r\n<a href=\"https://www.riot.today/\">RIOT (Research and Innovation on Territory)</a> is a laboratory engaged in pedagogy and research within the Institute of Architecture (ENAC) at the Swiss Federal Institute of Technology–EPFL, led by Charlotte Malterre-Barthes with Elif Erez, Flore Guichot, Jeremy Ratib, Summer Islam, Antoine Iweins, Kathy Kao, Nathalie Marj, Romain Dubetier-Grenier, Sylvie Clavel, and Saira Mohammed. Believing that the construction sector and design disciplines must pivot and wholeheartedly engage in the current social and climatic urgencies by rewiring themselves to face and repair the harm, RIOT utilizes tactics and strategies to decarbonize, decolonize, and depatriarchalize space production–by design. <br>\r\n </p>", "image_description": "Event poster", "creation_date": "2026-09-16T14:54:57", "last_modification_date": "2026-09-25T13:42:02", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "Foyer SG", "url_place_and_room": "", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "<a href=\"https://www.eca.ed.ac.uk/profile/dr-liam-ross\"><u>Liam Ross</u></a> is an architect and senior lecturer in Architectural Design at the University of Edinburgh, with a focus on building standardisation as a mode of architectural design, and in particular on fire-safety regulation. He also examines how those standards produce surprising side-effects as they are reinterpreted in practice. His book Pyrotechnic Cities: Architecture, Fire-Safety and Standardisation was published by Routledge in 2022, and describes the way that architectural design is an instrument of political agency. His work has been exhibited and published widely, including in Architectural Research Quarterly (arq), Arch+, and journalistic outlets such as Blueprint, Prospect, and Volume. Ross has experience of practice in the UK and US, including a period of 5 years with Malcolm Fraser Architects, and maintains a relationship with professional practice as co-founder of ESALA Projects, a consultancy offering pro-bono and for-fee design services to public and third-sector clients. His most recent work, published in January 2026 in Architectural Research Quarterly, includes a co-authored article with Jon Goodbun entitled ‘Design and the extended building site: Ecologies of production and the production of ecologies’, which reframes the building site as an 'extended' socioecological system reaching across the global supply chains, material extraction, and labour that construction depends on, arguing that building is an ecological and political process rather than a purely material one.", "organizer": "RIOT, MAS UTD", "contact": "Elif Erez, [email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "risk, territory, ecology, architecture, spatial justice, material supply chains, extraction", "file": "https://memento.epfl.ch/public/upload/files/2026PressurePointsPosterA3UPDATED_a2BW9qX.jpg", "icalendar_url": "https://memento.epfl.ch/event/export/121826/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/4/?format=api", "https://memento.epfl.ch/api/v1/mementos/32/?format=api" ] }, { "id": 72602, "title": "Pressure Points: Risk - Jess Myers / RIOT, MAS UTD", "slug": "pressure-points-risk-jess-myers-riot-mas-utd", "event_url": "https://memento.epfl.ch/event/pressure-points-risk-jess-myers-riot-mas-utd", "visual_url": "https://memento.epfl.ch/image/33846/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33846/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33846/max-size.jpg", "lang": "en", "start_date": "2026-11-16", "end_date": "2026-11-16", "start_time": "17:00:00", "end_time": "19:00:00", "description": "<p>“To emphasize (...) dubious uses of risk is perverse, a dirty way of talking about a<br>\r\nclean scientific subject”<br>\r\nMary Douglas, <em>Risk and Blame,</em> 36.<br>\r\n<br>\r\nAs the baseline condition of so many territories shaped by extractive industries, administrative delay, and climatic instability, risk is prevalent. Yet ecological risk—pollution, fires, floods, heatwaves, droughts—is still presented as problems to be solved rather than conditions to be inhabited. This also speaks to an outsourcing of risk through externalized consequences of spatial injustice. Banks, developers, material supply chains, normative institutions, subcontracting hierarchies —all contend with calculated risk. This edition of <u>Pressure Points</u> asks us to unpack what it means to live with the risk, how it is managed, commodified, quantified, invented, politicized, instrumentalized, tamed, and to think, design, cohabitate intellectually and physically with it. The assembled guests should help us think and build literacy toward developing tools for living within uncertain territories and futures.<br>\r\n<br>\r\n<u>Jess Myers</u><br>\r\nMonday, November 16, 17:00 CET<br>\r\n<br>\r\n<a href=\"https://soa.syr.edu/live/profiles/1181-jess-myers\"><u>Jess Myers</u></a> is an urbanist whose practice includes work as an editor, writer, podcaster and curator, and is a tenure-track Assistant Professor at Syracuse University. Previously, Myers was an assistant professor of architecture at the Rhode Island School of Design. She has worked as an archivist, translator and analyst in New York and Paris. Myers served as a co-steward of the Architecture Lobby’s New York chapter and as the series editor for SEIU’s book series, Taking Freedom. Her research takes many forms, including a variety of multimedia platforms, which she uses to explore politics and residency in urban conditions. Myers’ podcast, Here There Be Dragons focuses on the intersection of identity politics and security policy in public space through the eyes of New Yorkers, Parisians and Stockholmers. Myers’ work has been published in The Architect’s Newspaper, Log, The Funambulist Magazine, Failed Architecture, Avery Review, Dwell and l’Architecture d’Aujourd’hui. Her most recent exhibition, “A Pause Is Not A Break,“ was exhibited widely, including at the Rhode Island School of Design, the University of Iowa and Carleton University.<br>\r\n<br>\r\n<a href=\"https://www.riot.today/\">RIOT (Research and Innovation on Territory)</a> is a laboratory engaged in pedagogy and research within the Institute of Architecture (ENAC) at the Swiss Federal Institute of Technology–EPFL, led by Charlotte Malterre-Barthes with Elif Erez, Flore Guichot, Jeremy Ratib, Summer Islam, Antoine Iweins, Kathy Kao, Nathalie Marj, Romain Dubetier-Grenier, Sylvie Clavel, and Saira Mohammed. Believing that the construction sector and design disciplines must pivot and wholeheartedly engage in the current social and climatic urgencies by rewiring themselves to face and repair the harm, RIOT utilizes tactics and strategies to decarbonize, decolonize, and depatriarchalize space production–by design.<br>\r\n </p>", "image_description": "Event Poster", "creation_date": "2026-09-16T15:33:36", "last_modification_date": "2026-09-25T13:41:15", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "Foyer SG", "url_place_and_room": "", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "<a href=\"https://soa.syr.edu/live/profiles/1181-jess-myers\"><u>Jess Myers</u></a> is an urbanist whose practice includes work as an editor, writer, podcaster and curator, and is a tenure-track Assistant Professor at Syracuse University. Previously, Myers was an assistant professor of architecture at the Rhode Island School of Design. She has worked as an archivist, translator and analyst in New York and Paris. Myers served as a co-steward of the Architecture Lobby’s New York chapter and as the series editor for SEIU’s book series, Taking Freedom. Her research takes many forms, including a variety of multimedia platforms, which she uses to explore politics and residency in urban conditions. Myers’ podcast, Here There Be Dragons focuses on the intersection of identity politics and security policy in public space through the eyes of New Yorkers, Parisians and Stockholmers. Myers’ work has been published in The Architect’s Newspaper, Log, The Funambulist Magazine, Failed Architecture, Avery Review, Dwell and l’Architecture d’Aujourd’hui. Her most recent exhibition, “A Pause Is Not A Break,“ was exhibited widely, including at the Rhode Island School of Design, the University of Iowa and Carleton University.", "organizer": "RIOT, MAS UTD", "contact": "Elif Erez, [email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "risk, territory, ecology, architecture, spatial justice, material supply chains, extraction", "file": "https://memento.epfl.ch/public/upload/files/2026PressurePointsPosterA3UPDATED.jpg", "icalendar_url": "https://memento.epfl.ch/event/export/121831/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/4/?format=api", "https://memento.epfl.ch/api/v1/mementos/32/?format=api" ] }, { "id": 72621, "title": "ADSV Happy Hour", "slug": "adsv-happy-hour", "event_url": "https://memento.epfl.ch/event/adsv-happy-hour", "visual_url": "https://memento.epfl.ch/image/33970/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33970/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33970/max-size.jpg", "lang": "en", "start_date": "2026-10-08", "end_date": "2026-10-08", "start_time": "17:00:00", "end_time": "22:00:00", "description": "<div class=\"elementToProof\">\r\n<div class=\"elementToProof\">Hi everyone!</div>\r\n</div>\r\n\r\n<div class=\"elementToProof\"><br>\r\nFall is here, and so is our next happy hour! <br>\r\n </div>\r\n\r\n<div class=\"elementToProof\">Join us on Thursday, 8th of October at 17:00 in the SV Hall for a fall-themed evening hosted by the Paoli Lab, filled with seasonal drinks, cold beers and delicious autumn snacks! </div>\r\n\r\n<div class=\"elementToProof\"><br>\r\nSo bring your best autumn mood and come enjoy the season with us! <br>\r\n </div>\r\n\r\n<div class=\"elementToProof\">Looking forward to a lovely evening with all of you!</div>\r\n\r\n<div class=\"elementToProof\">Your ADSV Team</div>", "image_description": "ADSV Logo", "creation_date": "2026-09-18T11:38:41", "last_modification_date": "2026-10-02T14:28:17", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV Hall", "url_place_and_room": "", "url_online_room": "", "spoken_languages": [], "speaker": "", "organizer": "ADSV", "contact": "Eliane Duperrex ([email protected]) & Dominic Dall'Osto ([email protected])", "is_internal": "False", "theme": "", "vulgarization": { "id": 1, "fr_label": "Tout public", "en_label": "General public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "ADSV Happy Hour", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121861/", "category": { "id": 9, "code": "MANIF", "fr_label": "Événements festifs et culturels", "en_label": "Cultural events", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/9/?format=api" ] }, { "id": 72369, "title": "Mechanical forces as long-range organizers of cellular physiology", "slug": "mechanical-forces-as-long-range-organizers-of-cell", "event_url": "https://memento.epfl.ch/event/mechanical-forces-as-long-range-organizers-of-cell", "visual_url": "https://memento.epfl.ch/image/33626/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33626/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33626/max-size.jpg", "lang": "en", "start_date": "2026-10-16", "end_date": "2026-10-16", "start_time": "16:00:00", "end_time": "16:45:00", "description": "<p>In migrating cells, the GTPase Rac organizes a protrusive front, whereas Rho organizes a contractile back, yet how these GTPases segregate remains unclear. We leverage optogenetics, mechanical perturbations, and modeling to reveal a mechanochemical long-range mutual activation between front and back polarity programs that complements their known local mutual inhibition. Rac-driven protrusions increase membrane tension, triggering mTORC2-dependent Rho activation at the opposite side of the cell. Conversely, Rho-mediated contractility induces cortical-flow regulation of phosphoinositide signaling, promoting distal Rac activation. Our findings demonstrate how the actin cortex and plasma membrane interact as an integrated mechanochemical system for long-range Rac-Rho patterning. Efficient migration also requires polarized organization of the cell interior, with organelle positioning increasingly recognized as a key determinant of cell movement. Yet how this organization is established remains unclear. Building on our mechanochemical framework, we now investigate how actin-generated forces position organelles during migration and how disruption of this intracellular organization contributes to disease.<br>\r\n<br>\r\nWebsite of the De Belly lab: <a href=\"https://cri.utsw.edu/faculty/henry-de-belly/\">https://cri.utsw.edu/faculty/henry-de-belly/</a><br>\r\n<br>\r\nThis is part of the Physics of Living Systems monthly symposium: <a href=\"https://pols.epfl.ch/physics-of-living-systems-seminars/monthly-symposium/\">https://pols.epfl.ch/physics-of-living-systems-seminars/monthly-symposium/</a></p>", "image_description": "Dr. Henry De Belly, UTSW", "creation_date": "2026-08-19T11:02:03", "last_modification_date": "2026-08-19T12:10:32", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/7467019292", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Dr. Henry De Belly, UTSW", "organizer": "Dr. Juan Manuel García-Arcos, EPFL", "contact": "Dr. Juan Manuel García-Arcos, [email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "Mechanobiology, cell signalling, cell migration, mTORC2, Rho GTPases, cellular organization", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121471/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api" ] }, { "id": 72373, "title": "Lysosomes at the nexus of cellular quality control and metabolism", "slug": "lysosomes-at-the-nexus-of-cellular-quality-control", "event_url": "https://memento.epfl.ch/event/lysosomes-at-the-nexus-of-cellular-quality-control", "visual_url": "https://memento.epfl.ch/image/33629/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33629/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33629/max-size.jpg", "lang": "en", "start_date": "2026-10-15", "end_date": "2026-10-15", "start_time": "16:00:00", "end_time": "17:00:00", "description": "<p>Lysosomes sit at the crossroads of cellular catabolism and quality control, where they must dismantle chemically diverse cargo while preserving their own integrity. I will discuss two discoveries that reveal how lysosomes solve these complementary challenges and how their failure creates disease vulnerabilities. First, I will describe Lysosomal Leucine Aminopeptidase (LyLAP), an enzyme specialized to processively degrade the hydrophobic α-helices of transmembrane proteins. LyLAP is highly expressed in pancreatic ductal adenocarcinoma, where its loss causes hydrophobic peptides to accumulate, compromises lysosomal function, and ultimately leads to cancer cell death, revealing a potential vulnerability in tumors with elevated endocytic activity. I will then describe LASER, a damage-responsive protein assembly that couples lysosomal membrane injury to repair. At its core, the oligomeric protein TFG recognizes LC3/GABARAP proteins conjugated to damaged lysosomes and recruits the ESCRT machinery to restore membrane integrity. Neurodegenerative disease-associated mutations in TFG disrupt this process, linking defective lysosomal repair to human disease. Together, these findings reveal lysosomes as dynamic systems that coordinate cargo degradation with membrane surveillance and repair to maintain cellular homeostasis. <br>\r\n<br>\r\nMore about Dr. Aakriti Jain's lab at UTSW: <a href=\"https://aakritijainlab.com/\">https://aakritijainlab.com/</a></p>", "image_description": "Dr. Aakriti Jain", "creation_date": "2026-08-19T11:24:24", "last_modification_date": "2026-09-21T16:54:33", "link_label": "", "link_url": "", "canceled": "False", "cancel_reason": "", "place_and_room": "SV 1717", "url_place_and_room": "https://plan.epfl.ch/?room==SV%201717", "url_online_room": "https://epfl.zoom.us/j/7467019292", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Dr. Aakriti Jain, UTSW", "organizer": "Dr. Juan Manuel García-Arcos", "contact": "Dr. Juan Manuel García-Arcos, [email protected]", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "ESCRT, Lysosomal repair, organelle dynamics, Lysosomal Leucine Aminopeptidase, transmembrane protein degradation", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121477/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/9/?format=api", "https://memento.epfl.ch/api/v1/mementos/111/?format=api" ] }, { "id": 72705, "title": "The uncomfortable truth", "slug": "the-uncomfortable-truth", "event_url": "https://memento.epfl.ch/event/the-uncomfortable-truth", "visual_url": "https://memento.epfl.ch/image/33930/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33930/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33930/max-size.jpg", "lang": "en", "start_date": "2026-10-28", "end_date": "2026-10-28", "start_time": "17:30:00", "end_time": "19:00:00", "description": "<p>Behind every fast-growing startup lies a story of experimentation, setbacks, and continuous reinvention. Drawing on the experience of <a href=\"https://www.linkedin.com/in/vbieri/\"><strong>Vincent Bieri</strong></a><strong>, co-founder of Nexthink - the Swiss-born technology company that grew into a unicorn - </strong> this seminar will look beyond headlines and valuations to examine the challenges, tough decisions, and perseverance that shape the entrepreneurial journey.<br>\r\n<br>\r\nThe Viewpoint Series, is a new entrepreneurship seminar series designed to expose students and scientists to real-world perspectives from founders, operators, and investors.<br>\r\nSupported by <a href=\"e4s.center\">E4S </a>and organized by <a href=\"https://www.epfl.ch/schools/cdm/\">EPFL - College of Management of Technology</a>, and <a href=\"https://www.epfl.ch/schools/cdm/ehub/\">EPFL Entrepreneurship Education Hub</a>, it brings together experienced practitioners to share candid perspectives on:\r\n</p><ul>\r\n\t<li>Navigating uncertainty and key transitions</li>\r\n\t<li>Critical inflection points in building ventures</li>\r\n\t<li>Lessons learned along the entrepreneurial journey</li>\r\n</ul>\r\n <br>\r\nCombining inspirational talks with interactive discussions, the series encourages reflection and dialogue on what it truly means to build and scale ventures.<br>\r\n <br>\r\n<br>\r\n ", "image_description": "", "creation_date": "2026-09-29T10:04:56", "last_modification_date": "2026-10-01T09:54:12", "link_label": "Registration", "link_url": "https://forms.cloud.microsoft/Pages/DesignPageV2.aspx?origin=NeoPortalPage&subpage=design&id=alXC9vvEsUqix54iDfEcQ3T6XowngO9FnfVR8iOh7ptUNEJYQVhSS1pCNlg2Q0RDNUg1S1g4SVVFVC4u", "canceled": "False", "cancel_reason": "", "place_and_room": "CM 1 3", "url_place_and_room": "https://plan.epfl.ch/?room==CM%201%203", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "<a href=\"https://www.linkedin.com/in/vbieri/\">Vincent Bieri, co-founder of Nexthink and Role Model for Project Switzerland</a>", "organizer": "", "contact": "Davide Bavato", "is_internal": "False", "theme": "", "vulgarization": { "id": 2, "fr_label": "Public averti", "en_label": "Informed public" }, "registration": { "id": 1, "fr_label": "Sur inscription", "en_label": "Registration required" }, "keywords": "", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121981/", "category": { "id": 1, "code": "CONF", "fr_label": "Conférences - Séminaires", "en_label": "Conferences - Seminars", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/3/?format=api", "https://memento.epfl.ch/api/v1/mementos/4/?format=api", "https://memento.epfl.ch/api/v1/mementos/5/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/38/?format=api", "https://memento.epfl.ch/api/v1/mementos/145/?format=api" ] }, { "id": 72214, "title": "Do Robots Dream of Construction Sites? / ARCHIZOOM x CRCL", "slug": "do-robots-dream-of-construction-sites-archizoom--3", "event_url": "https://memento.epfl.ch/event/do-robots-dream-of-construction-sites-archizoom--3", "visual_url": "https://memento.epfl.ch/image/33494/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33494/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33494/max-size.jpg", "lang": "en", "start_date": "2026-09-09", "end_date": "2026-12-05", "start_time": null, "end_time": null, "description": "<strong>DO ROBOTS DREAM OF CONSTRUCTION SITES?<br>\r\n09.09-05.12.2026<br>\r\n<br>\r\nOpening Tuesday 8 September<br>\r\n6.15pm – </strong>Discussion between Stefana Parascho and Aude Billard, moderated by Pier Vittorio Aureli<br>\r\n<strong>7.30pm –</strong> Opening doors and aperitive<br>\r\n<br>\r\nWhat if robots didn’t replace us, but worked alongside us? Robots are capable of assembling, analysing, experimenting and learning from their mistakes. Could they take on construction work without replacing human labour? Research carried out by the CRCL – Lab for Creative Computation at EPFL explores a form of collaboration between humans and machines that departs from the traditional promise of automation. It opens the way to more inclusive building sites and non-standardised, more environmentally friendly architecture that goes beyond the mere logic of replacement and productivity. <br>\r\n<br>\r\n<strong>An exhibition produced in collaboration with the <a href=\"https://www.crclcrclcrcl.org/\">CRCL – Lab for Creative Computation</a>, led by Stefana Parascho</strong>", "image_description": "", "creation_date": "2026-07-07T11:36:24", "last_modification_date": "2026-07-13T17:08:03", "link_label": "Do Robots Dream of Construction Sites", "link_url": "https://www.epfl.ch/campus/art-culture/museum-exhibitions/archizoom/fr/do-robots-dream-of-construction-sites/", "canceled": "False", "cancel_reason": "", "place_and_room": "Archizoom", "url_place_and_room": "https://plan.epfl.ch/?room==SG%201212", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/1/?format=api", "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "CRCL - Lab for Creative Computation", "organizer": "Archizoom", "contact": "Cyril Veillon, Solène Hoffmann", "is_internal": "False", "theme": "", "vulgarization": { "id": 1, "fr_label": "Tout public", "en_label": "General public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "Architecture, Technology, Construction, Robotic, Robots, Travail, Labor, Durability", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121235/", "category": { "id": 5, "code": "EXPO", "fr_label": "Expositions", "en_label": "Exhibitions", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/4/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/22/?format=api", "https://memento.epfl.ch/api/v1/mementos/32/?format=api", "https://memento.epfl.ch/api/v1/mementos/45/?format=api", "https://memento.epfl.ch/api/v1/mementos/145/?format=api", "https://memento.epfl.ch/api/v1/mementos/417/?format=api" ] }, { "id": 72280, "title": "Do Robots Dream of Construction Sites? / ARCHIZOOM x CRCL", "slug": "do-robots-dream-of-construction-sites-archizoom--2", "event_url": "https://memento.epfl.ch/event/do-robots-dream-of-construction-sites-archizoom--2", "visual_url": "https://memento.epfl.ch/image/33548/200x112.jpg", "visual_large_url": "https://memento.epfl.ch/image/33548/720x405.jpg", "visual_maxsize_url": "https://memento.epfl.ch/image/33548/max-size.jpg", "lang": "en", "start_date": "2026-10-13", "end_date": "2026-10-24", "start_time": "17:30:00", "end_time": "18:30:00", "description": "<strong>Tuesday 13 October 2026 </strong><br>\r\n<strong>5.30pm –</strong> <a href=\"https://forms.gle/8mG39FYernNXnsJG6\">Guided tour</a> of the exhibition Do Robots Dream of Construction Sites?<br>\r\n<br>\r\nWhat if robots didn’t replace us, but worked alongside us? Robots are capable of assembling, analysing, experimenting and learning from their mistakes. Could they take on construction work without replacing human labour? Research carried out by the CRCL – Lab for Creative Computation at EPFL explores a form of collaboration between humans and machines that departs from the traditional promise of automation. It opens the way to more inclusive building sites and non-standardised, more environmentally friendly architecture that goes beyond the mere logic of replacement and productivity. <br>\r\n<br>\r\n<strong>This event will be followed by the opening of the installation NO/NC (Normally Open, Normally Closed) by the artists AATB, supported and organized in collaboration with Usinesonore and Pôle Culture (VPI).</strong>", "image_description": "", "creation_date": "2026-07-27T16:05:04", "last_modification_date": "2026-09-15T17:26:38", "link_label": "Vernissage Julian Sartorius x AATB", "link_url": "https://www.epfl.ch/campus/art-culture/museum-exhibitions/archizoom/fr/no-nc-normally-open-normally-closed-aatb-2/", "canceled": "False", "cancel_reason": "", "place_and_room": "Hall SG", "url_place_and_room": "https://plan.epfl.ch/?room==SG%20294.22", "url_online_room": "", "spoken_languages": [ "https://memento.epfl.ch/api/v1/spoken_languages/1/?format=api", "https://memento.epfl.ch/api/v1/spoken_languages/2/?format=api" ], "speaker": "Stefana Parascho", "organizer": "Archizoom", "contact": "Cyril Veillon, Solène Hoffmann", "is_internal": "False", "theme": "", "vulgarization": { "id": 1, "fr_label": "Tout public", "en_label": "General public" }, "registration": { "id": 3, "fr_label": "Entrée libre", "en_label": "Free" }, "keywords": "architecture, performance, technology, robotics", "file": null, "icalendar_url": "https://memento.epfl.ch/event/export/121333/", "category": { "id": 9, "code": "MANIF", "fr_label": "Événements festifs et culturels", "en_label": "Cultural events", "activated": true }, "academic_calendar_category": null, "domains": [], "mementos": [ "https://memento.epfl.ch/api/v1/mementos/1/?format=api", "https://memento.epfl.ch/api/v1/mementos/4/?format=api", "https://memento.epfl.ch/api/v1/mementos/6/?format=api", "https://memento.epfl.ch/api/v1/mementos/8/?format=api", "https://memento.epfl.ch/api/v1/mementos/22/?format=api", "https://memento.epfl.ch/api/v1/mementos/32/?format=api", "https://memento.epfl.ch/api/v1/mementos/145/?format=api" ] } ] }
