retrieve:
Return the details about the given Event id.

list:
List all Event objects.

GET /api/v1/events/?format=api&offset=210&ordering=-event__end_date
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

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            "id": 72685,
            "title": "IMX Colloquium - Towards life-inspired soft matter dynamics and functionalities",
            "slug": "imx-colloquium-towards-life-inspired-soft-matter-d",
            "event_url": "https://memento.epfl.ch/event/imx-colloquium-towards-life-inspired-soft-matter-d",
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            "start_date": "2026-10-12",
            "end_date": "2026-10-12",
            "start_time": "13:15:00",
            "end_time": "14:15:00",
            "description": "<p>Biological systems have already paved several routes for bioinspired materials, e.g., for structural colours, wetting, adhesion, and mechanical properties. They have largely involved equilibrium or kinetically trapped properties. By contrast, biological systems allowing multifunctional properties are characteristically dissipatively and dynamically adaptive and incorporate homeostatic feedback mechanisms to regulate the dynamic states. They also typically use signal transduction to mediate the signal from the sensory elements to the responsive sites, unlike the classic man-made stimuli responsive materials. These concept suggest avenues towards more complex life-like functions in soft matter. Herein, optically driven hydrogel systems are presented to drive homeostatically controlled thermal oscillations and to mediate signal transduction via thermal intermediate signalling (1). On the other hand, biological magnetoreception in elasmobranch organisms involves electromagnetic induction (EMI) and suggests avenues for bioinspired electrical signal transductions.  We show magnetic profile recognition of translocated magnetically encoded soft matter objects using electrical intermediate signaling by EMI and decoding the magnetic information with machine learning (2). Combination of high stiffness and promoted dynamics for self-healing has turned challenging to combine. Self-healing hydrogels, still combining high tensile stiffness close to that of skin were shown by using polymers upon nanoconfinement in 2D-nanosheet layered confinements (3). Finally, we show trainable actuations in bilayer gel actuators (4). Ever more complex responses can be created, such as mimicking the Pavlovian classical conditioning (5), all paving ways for growingly life-like functions for soft robotics and interfacing with biology.<br>\r\n<br>\r\n1.  H. Zhang, H. Zeng, A. Eklund, H. Guo, A. Priimagi, O. Ikkala, Feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction, <em>Nat. Nano</em>, <strong>17</strong>, 1303 (2022).<br>\r\n2.  Z. Miao, X. Hu, K. Liu, S. Hu, G. Yan, H. Tan, O. Ikkala, Z. P. Lv, B. Peng, Bioinspired sensory transduction for magnetic profile recognition and encryption, <em>Adv. Mat.</em> <strong>38</strong> e15994 (2026).<br>\r\n3.   C. Liang, V. Dudko, O. Khoruzhenko, X. Hong, Z.-P. Lv, J. Breu, O. Ikkala, H. Zhang, Stiff and self-healing hydrogels by polymer entanglements in co-planar nanoconfinement, <em>Nat. Mater.</em> <strong>24</strong>, 599 (2025).<br>\r\n4.  S. Hu, Y. Fang, C. Liang, M. Turunen, O. Ikkala, H. Zhang, Thermally trainable dual network hydrogels, <em>Nat. Commun.</em>, <strong>14</strong>, 3717 (2023).<br>\r\n5. H. Zhang, H. Zeng, A. Priimagi, O. Ikkala, Programmable responsive hydrogels with classical conditioning algorithm, <em>Nat. Commun.</em>, <strong>10</strong>, 3267 (2019).</p>",
            "image_description": "",
            "creation_date": "2026-09-28T09:13:29",
            "last_modification_date": "2026-10-06T08:54:13",
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            "speaker": "Prof. Olli Ikkala, Aalto University, Department of Applied Physics, Espoo, Finland",
            "organizer": "Prof. Gregor Jotzu, Prof. Esther Amstad &amp; Prof. Fabien Sorin",
            "contact": "Prof. Gregor Jotzu, Prof. Esther Amstad &amp; Prof. Fabien Sorin",
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            "id": 72689,
            "title": "Apprentissage sur des graphes, modèles d'attention.",
            "slug": "apprentissage-sur-des-graphes-modeles-d-attentio-2",
            "event_url": "https://memento.epfl.ch/event/apprentissage-sur-des-graphes-modeles-d-attentio-2",
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            "start_date": "2026-10-12",
            "end_date": "2026-10-12",
            "start_time": "15:15:00",
            "end_time": null,
            "description": "<p>Thesis Director: Prof. L. Zdeborová,<br>\r\nComputer and Communication Sciences doctoral program<br>\r\nThesis Nr. 11792<br>\r\n<br>\r\nTo take part in the public defense, please contact directly the speaker</p>",
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            "creation_date": "2026-09-28T12:45:24",
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            "speaker": "<a href=\"mailto:[email protected]\"><strong>Odilon DURANTHON</strong></a>",
            "organizer": "",
            "contact": "<a href=\"mailto:[email protected]\"><strong>Odilon DURANTHON</strong></a><br>\r\n ",
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            "keywords": "EDIC",
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            "id": 71387,
            "title": "Unearthed, by Rahel Oberhummer - Exhibition",
            "slug": "unearthed-by-rahel-oberhummer-exhibition",
            "event_url": "https://memento.epfl.ch/event/unearthed-by-rahel-oberhummer-exhibition",
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            "lang": "en",
            "start_date": "2026-05-07",
            "end_date": "2026-10-11",
            "start_time": "07:00:00",
            "end_time": "23:59:00",
            "description": "<p>Le projet <em>Unearthed</em> de l’artiste <a href=\"https://www.raheloberhummer.ch/\">Rahel Oberhummer</a> est une aventure visuelle et scientifique au cœur du développement de micro-organismes contenus dans le pergélisol de la montagne Muot da Barba Peider (Schafberg) en Engadine et collectés par l'Institut fédéral de recherches sur la forêt, la neige et le paysage (WSL). Cette collection préserve des micro-organismes provenant de régions menacées telles que les Alpes et l'Arctique et compte déjà plus de 2000 spécimens.<br>\r\n<br>\r\nL’artiste a sélectionné des levures, bactéries et champignons souvent vieux de 12’000 ans, qu’elle a cultivés dans son propre studio et photographiés tous les deux jours. Les différents micro-organismes sont déposés sur un fond d’agar pour qu’ils puissent se développer. Leur évolution est rapide et hasardeuse. La documentation est méthodique : plus de 13'300 photographies ont été prises représentant des instantanés de matière vivante.<br>\r\n<br>\r\nDeux séries de photographies ont été produites : l’une se concentre sur des monocultures, dans lesquelles une souche microbienne sélectionnée occupe une boîte de Pétri et se propage largement. En adaptant les méthodes d'inoculation et les milieux de culture, différentes impulsions sont déclenchées. La deuxième série fait cohabiter plusieurs organismes différents. La lutte pour les nutriments dans le milieu de culture ainsi que les symbioses qui peuvent se développer entre les microbes sont documentées. La pratique d’atelier se mêle à la pratique de laboratoire.<br>\r\n<br>\r\n<strong>L’exposition</strong><br>\r\n<br>\r\nL’exposition<em> Unearthed</em> présente 18 photographies de plusieurs micro-organismes différents évoluant dans les boîtes circulaires qui les abritent. Filaments, textures, entrelacs, pointillés, cercles produisent des configurations abstraites spectaculaires. Les couleurs enchantent et vivifient les formes en turbulente circulation et en constante métamorphose. Les photographies pointent le sublime de l’extraordinaire variété des cellules : la naissance du vivant.<br>\r\nLes photographies de Rahel Oberhummer révèlent deux nécessités indissociables : d’une part celle de comprendre le vivant même dans ses organismes les plus simples et d’autre part de le préserver. Parallèlement, il s’agit de créer des images qui manifestent la qualité visuelle des formes et des couleurs de ces micro-organismes. Notre rapport à la nature exige l’admiration de sa beauté. Aujourd’hui, des artistes comme Rahel Oberhummer s’engagent dans une double mission : participer activement à des processus scientifiques et créer des images sensibles tout autant que savantes.<br>\r\n<br>\r\n<strong>Collaborations</strong><br>\r\n<br>\r\nSérie photographique réalisée en collaboration avec l’Institut fédéral de recherches sur la forêt, la neige et le paysage (WSL). Unité : Biodiversité et écologie de la conservation.<br>\r\nDr. Beat Frey, Dr. Joel Rüthi, Dr. Ivano Brunner, Beat Stierli<br>\r\n<br>\r\n<strong>Eléments biographiques</strong><br>\r\n<br>\r\nRahel Oberhummer (*1991, Loèche-les-Bains) est diplômée de la HEAD, Genève. Elle a étudié aussi à la Royal Danish Academy of Fine Arts, Copenhague, à la Hochschule für Kunst und Design de Lucerne et au Billy Blue College of Design à Sydney. Au début de l’année 2026, elle a obtenu une résidence de trois mois à Hanoï, au Vietnam, dans le cadre d’un séjour de recherche soutenu par Pro Helvetia et accueilli par l’espace Exutoire. Elle vit et travaille à Vevey.<br>\r\nLa relation entre les structures sociales humaines et les formes de vie non humaines est au cœur de son approche artistique. Rahel Oberhummer se concentre sur les interactions subtiles entre les humains et l'environnement, avec une attention soutenue pour les écosystèmes dont nous dépendons et que nous mettons pourtant en danger. Des questions se posent, que l'artiste explore à travers une recherche scientifique autant qu’artistique.<br>\r\n<br>\r\n<a href=\"https://www.raheloberhummer.ch/\"><strong>&gt;&gt;&gt; Site web de l'artiste Rahel Oberhummer</strong></a><br>\r\n<br>\r\n<strong>Vernissage</strong> le jeudi 7 mai 2026 à 18 :30 <br>\r\n<strong>Exposition visible jusqu’au 11 octobre 2026<br>\r\nHall du RLC / entrée libre</strong><br>\r\n<br>\r\n<u>Image</u> :<em> </em>Dioszegia patagonica 001, Pochonia/Metacordyceps chlamydosporia 205, Pseudogymnoascus pannorum 511, Potato Dextrose Agar with sepia ink, 2022.</p>",
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            "creation_date": "2026-03-16T17:17:43",
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            "speaker": "<a href=\"https://www.raheloberhummer.ch/\">Rahel Oberhummer, artiste</a>",
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        {
            "id": 72499,
            "title": "Musical Composition: Playing with the Verbier Festival Archives",
            "slug": "musical-composition-playing-with-the-verbier-festi",
            "event_url": "https://memento.epfl.ch/event/musical-composition-playing-with-the-verbier-festi",
            "visual_url": "https://memento.epfl.ch/image/33787/200x112.jpg",
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            "lang": "en",
            "start_date": "2026-10-10",
            "end_date": "2026-10-10",
            "start_time": "16:00:00",
            "end_time": "20:00:00",
            "description": "<p>Thanks to a donation from the Claude Latour Foundation, the Pôle Culture (VPI) is organizing a master class followed by a public concert based on the Verbier Festival archives, which are being digitized at <a href=\"http://www.epfl.ch/research/domains/centre-innovation-patrimoines-culturels/\">EPFL by the EPFL Cultural Heritage &amp; Conservation Platform (CHC)</a>.<br>\r\n<br>\r\nDuring the masterclass, the selected students are invited to create a musical piece lasting no more than 5 minutes in the style, aesthetic, and genre of their choice (jazz, rap, rock, metal, classical, etc.). At the end of the day, the pieces will be presented to the public, accompanied by comments from a panel of experts. <br>\r\n<br>\r\n<strong>PROGRAM:</strong>\r\n</p><ul>\r\n\t<li><strong>10:00–16:00: Masterclass</strong> (<a href=\"https://forms.cloud.microsoft/e/A0FMYfPjg1\">registration required</a>)<br>\r\n\t </li>\r\n\t<li><strong>16:00–16:15: Welcome for the audience</strong></li>\r\n\t<li>16:15–17:45: Listening to the compositions with commentary from experts</li>\r\n\t<li>17:45–18:15: Submit a music sample of your composition (max. 5 min, in MP3 format)</li>\r\n\t<li><strong>18:30: Aperitif with the audience</strong> (<a href=\"http://forms.cloud.microsoft/e/z8TTfURvwX\">registration required</a>)</li>\r\n</ul>\r\n---<br>\r\n<strong>MASTERCLASS:</strong><br>\r\nThe Verbier Festival is opening its archives and making audio tracks from classical music concerts available. Participants will be able to transform, reinterpret, and reinvent these tracks to create a personal, original 5-minute piece in any musical style.<br>\r\n<br>\r\nThroughout the process, four experts will guide the participants, sharing their advice and helping each person bring their project to life.<br>\r\n<br>\r\n<strong>The Experts:</strong><br>\r\n<a href=\"http://people.epfl.ch/alain.dufaux\">Alain Dufaux</a>, Director of the EPFL CHC Platform—Cultural Heritage &amp; Conservation<br>\r\n<a href=\"https://edpub.unil.ch/interpub/noauth/php/Un/UnPers.php?PerNum=64542&amp;LanCode=37\">Constance Frei</a>, musicologist, professor at UNIL/EPFL<br>\r\n<a href=\"http://hem.hesge.ch/la-hem/alumniae/portrait-alumniae/charlotte-graber-musicologue-bibliothecaire\">Charlotte Graber</a>, musicologist at HEM, Geneva <br>\r\n<a href=\"http://verbierfestival.com/musician/mcholm-stephen/\">Stephen McHolm</a>, Director of the Verbier Festival Academy <br>\r\n<br>\r\n<strong>Practical Information:</strong>\r\n\r\n<ul>\r\n\t<li>Open to a maximum of 6 EPFL students</li>\r\n\t<li>Saturday, October 10, from 10 a.m. to 8 p.m. at the Montreux Jazz Café</li>\r\n\t<li>Prerequisites: Submit a music sample of your composition (max. 5 min, in MP3 format)</li>\r\n\t<li>Technical requirements: bring your own computer and headphones</li>\r\n</ul>\r\n<a href=\"https://forms.cloud.microsoft/e/A0FMYfPjg1\"><strong>&gt;&gt;&gt; Register for the Masterclass</strong></a> (deadline: October 5, at noon)<br>\r\n<br>\r\n---<br>\r\n<strong>EPFL CHC and the Verbier Festival:</strong><br>\r\nThe EPFL Cultural Heritage Conservation Platform (CHC) was established at EPFL in 2010 under the name “Metamedia Center.” For the past 16 years, it has pursued a dual mission: to digitize and preserve audiovisual collections and heritage of major significance in Switzerland and around the world, and to enrich and bring them to life through research and innovation projects conducted in EPFL’s laboratories, startups, and in collaboration with EPFL partners. The collections thus assembled become true research infrastructures: they provide a unique resource for education and research, accessible to students as well as to innovation communities at EPFL and around the world.<br>\r\n<br>\r\nIt was with this goal in mind that EPFL and the <a href=\"http://verbierfestival.com/\">Verbier Festival</a> launched the Verbier Festival Collection project in 2021. The project aims to preserve and promote the festival’s heritage, with the goal of rekindling younger generations’ interest in classical music.<br>\r\n<br>\r\nA pioneer since 1994, the Verbier Festival is the first festival in the world to have recorded all of its concerts. This exceptional collection now includes 3,000 hours of audio recordings, more than 1,000 hours of video, 12,000 historical photographs, archival documents, and a collection of annotated sheet music. It serves as a unique resource for research, innovation, and cultural transmission. As part of this collaboration, EPFL students are invited—upon registration and following a selection process—to participate in a master class during which they will draw on part of this heritage to create a musical work, which they will then present to an audience and a jury.<br>\r\n<br>\r\n---<br>\r\n<strong>Partners: </strong>Claude Latour Foundation, Verbier Festival, CHC Platform—Cultural Heritage &amp; Conservation at EPFL, UNIL, Montreux Jazz Café, NAGRA <br>\r\n<br>\r\n<strong>&gt;&gt;&gt; Free admission; <a href=\"http://forms.cloud.microsoft/e/z8TTfURvwX\">aperitif available with registration</a></strong><br>\r\n \r\n<figure class=\"image\"><a href=\"https://www.epfl.ch/campus/art-culture/fr/les-culturelles/les-culturelles-dautomne-2026/\"><img alt=\"Programme complet des Culturelles\" height=\"182\" src=\"https://www.epfl.ch/campus/art-culture/wp-content/uploads/2026/09/LES_CULTURELLES_1920x1080_programme_complet.png\" width=\"600\"></a>\r\n\r\n<figcaption>© 2026 EPFL, Laura Persat</figcaption>\r\n</figure>",
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            "speaker": "<a href=\"https://people.epfl.ch/alain.dufaux\">Alain Dufaux</a>, directeur de la Plateforme EPFL CHC - Cultural Heritage &amp; Conservation ; <a href=\"https://applicationspub.unil.ch/interpub/noauth/php/Un/UnPers.php?PerNum=64542&amp;LanCode=37\">Constance Frei</a>, musicologue, professeure UNIL/EPFL ; <a href=\"https://hem.hesge.ch/la-hem/alumniae/portrait-alumniae/charlotte-graber-musicologue-bibliothecaire\">Charlotte Graber</a>, musicologue HEM, Genève ; <a href=\"https://verbierfestival.com/musician/mcholm-stephen/\">Stephen McHolm</a>, directeur de la Verbier Festival Academy ",
            "organizer": "<a href=\"https://www.epfl.ch/campus/art-culture/fr/les-culturelles/\">Festival Les Culturelles</a> (Pôle Culture VPI)",
            "contact": "<a href=\"https://people.epfl.ch/veronique.mauron\">Véronique Mauron Layaz</a>",
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        {
            "id": 70656,
            "title": "Innovate with AI and Tech",
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            "title": "G protein-coupled receptors functional dynamics revealed by experimental and computational structural data",
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            "description": "<p>You can apply to participate and find all the relevant information (speakers, abstracts, program,...) on the event website: <a href=\"https://www.cecam.org/workshop-details/g-protein-coupled-receptors-functional-dynamics-revealed-by-experimental-and-computational-structural-data-1488\">https://www.cecam.org/workshop-details/g-protein-coupled-receptors-functional-dynamics-revealed-by-experimental-and-computational-structural-data-1488</a>.<br>\r\n<br>\r\nRegistration is required to attend the full event, take part in the social activities and present a poster at the poster session (if any).  However, the EPFL community is welcome to attend specific lectures without registration if the topic is of interest to their research. Do not hesitate to contact the <a href=\"mailto:[email protected]\">CECAM Event Manager</a> if you have any question.<br>\r\n<br>\r\n<strong>Description</strong><br>\r\n<br>\r\nG protein-coupled receptors (GPCRs) represent a vast and diverse class of transmembrane proteins that orchestrate a wide range of physiological processes by responding to both endogenous and exogenous ligands [1,2]. These receptors are essential to critical functions such as metabolism, immune regulation, neuronal signaling, and sensory perception - including vision and olfaction. Due to their physiological relevance and membrane accessibility, GPCRs are the targets of approximately 34% of all prescribed medications, accounting for nearly 27% of the global pharmaceutical market [3]. <br>\r\nDespite their pharmaceutical importance, key aspects of GPCR function remain elusive. The canonical activation model posits that agonist binding to the extracellular orthosteric site triggers allosteric changes - most notably, the outward displacement of transmembrane helices 5 (TM5) and 6 (TM6) on the intracellular side - ultimately leading to receptor activation [2-4]. However, recent evidence suggests a more nuanced mechanism. In several GPCRs, activation appears to involve cooperative engagement between the agonist and the G protein. For example, the G protein may disrupt an \"inactivating ionic lock\" - a salt bridge between TM3 and TM6 - while the agonist stabilizes the active conformation. In some receptors, this is complemented by the formation of an “activating ionic lock” between TM5 and TM6 [5-8]. These dual contributions are considered thermodynamically essential for full activation [7].<br>\r\nAdding further complexity, GPCR activity is regulated by conformational microswitches and finely tuned intra-protein interaction networks. These dynamic rearrangements are difficult to capture and often elude direct correlation with functional outcomes. Moreover, allosteric ligands - which bind sites distinct from the orthosteric pocket - are being increasingly identified [9-12], along with small molecules capable of biased signaling, i.e., preferential activation of specific intracellular pathways [11-13, 16, 17]. These findings reveal a rich and underexplored conformational landscape that governs GPCR signaling. In addition, native membrane components—such as lipids and interacting proteins, including GPCR oligomers—are known to significantly modulate receptor function [11, 18-22].<br>\r\nTo disentangle these intricacies, computational modeling has become indispensable, offering atomistic insight into GPCR conformational dynamics and mechanistic understanding [1-2, 7, 11, 14, 16–21, 23]. Nevertheless, key questions remain - particularly regarding the structural basis of biased signaling, strategies for leveraging allosteric networks in pharmacology, and the modulatory role of the lipid environment. Addressing these gaps is crucial for both fundamental biology and the rational design of next-generation GPCR-targeting drugs with improved selectivity and safety profiles. <br>\r\nThese scientific challenges form the foundation of our upcoming workshop, which will focus on the latest experimental and computational approaches for studying the functional dynamics of GPCRs. Given the profound health, economic, and societal implications of modulating these receptors with precision, we aim to strengthen the interdisciplinary nature of the event by increasing the representation of experimental research and integrating cutting-edge artificial intelligence applications into the program.<br>\r\nBuilding upon the success of the 2022 and 2024 editions - which led to new collaborations and a landmark publication in <em>Nature Reviews Drug Discovery</em> [24] - our goal is to further enhance communication and collaboration between experimentalists and theoreticians. The workshop will serve as a reference point for young scientists and students, offering a platform to interact with leading international experts. We are confident that this initiative will foster insightful discussions and contribute meaningfully to advancing the field of GPCR pharmacology.<br>\r\n<br>\r\n<strong>References</strong><br>\r\n<br>\r\n<a href=\"https://doi.org/10.1038/nrd.2017.229\" target=\"_blank\">[1] J. Smith, R. Lefkowitz, S. Rajagopal, Nat. Rev. Drug. Discov., <strong>17</strong>, 243-260 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41573-024-01083-3\" target=\"_blank\">[2] P. Conflitti, E. Lyman, M. Sansom, P. Hildebrand, H. Gutiérrez-de-Terán, P. Carloni, T. Ansell, S. Yuan, P. Barth, A. Robinson, C. Tate, D. Gloriam, S. Grzesiek, M. Eddy, S. Prosser, V. Limongelli, Nat. Rev. Drug. Discov., <strong>24</strong>, 251-275 (2025)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41589-024-01682-6\" target=\"_blank\">[3] L. Picard, A. Orazietti, D. Tran, A. Tucs, S. Hagimoto, Z. Qi, S. Huang, K. Tsuda, A. Kitao, A. Sljoka, R. Prosser, Nat. Chem. Biol., <strong>21</strong>, 71-79 (2024)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.drudis.2020.10.006\" target=\"_blank\">[4] B. Huang, C. St. Onge, H. Ma, Y. Zhang, Drug Discovery Today, <strong>26</strong>, 189-199 (2021)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41467-023-42082-z\" target=\"_blank\">[5] D. Di Marino, P. Conflitti, S. Motta, V. Limongelli, Nat. Commun., <strong>14</strong>, 6439 (2023)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.ceb.2018.10.007\" target=\"_blank\">[6] G. Milligan, R. Ward, S. Marsango, Current Opinion in Cell Biology, <strong>57</strong>, 40-47 (2019)</a><br>\r\n<a href=\"https://doi.org/10.7554/elife.73901\" target=\"_blank\">[7] S. Huang, O. Almurad, R. Pejana, Z. Morrison, A. Pandey, L. Picard, M. Nitz, A. Sljoka, R. Prosser, eLife, <strong>11</strong>, (2022)</a><br>\r\n<a href=\"https://doi.org/10.1146/annurev-pharmtox-010919-023411\" target=\"_blank\">[8] A. Duncan, W. Song, M. Sansom, Annu. Rev. Pharmacol. Toxicol., <strong>60</strong>, 31-50 (2020)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41467-025-60003-0\" target=\"_blank\">[9] A. Morales-Pastor, T. Miljuš, M. Dieguez-Eceolaza, T. Stępniewski, V. Ledesma-Martin, F. Heydenreich, T. Flock, B. Plouffe, C. Le Gouill, J. Duchaine, D. Sykes, C. Nicholson, E. Koers, W. Guba, A. Rufer, U. Grether, M. Bouvier, D. Veprintsev, J. Selent, Nat. Commun., <strong>16</strong>, 5265 (2025)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41586-022-05588-y\" target=\"_blank\">[10] A. Faouzi, H. Wang, S. Zaidi, J. DiBerto, T. Che, Q. Qu, M. Robertson, M. Madasu, A. El Daibani, B. Varga, T. Zhang, C. Ruiz, S. Liu, J. Xu, K. Appourchaux, S. Slocum, S. Eans, M. Cameron, R. Al-Hasani, Y. Pan, B. Roth, J. McLaughlin, G. Skiniotis, V. Katritch, B. Kobilka, S. Majumdar, Nature, <strong>613</strong>, 767-774 (2022)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41467-022-31652-2\" target=\"_blank\">[11] M. Wall, E. Hill, R. Huckstepp, K. Barkan, G. Deganutti, M. Leuenberger, B. Preti, I. Winfield, S. Carvalho, A. Suchankova, H. Wei, D. Safitri, X. Huang, W. Imlach, C. La Mache, E. Dean, C. Hume, S. Hayward, J. Oliver, F. Zhao, D. Spanswick, C. Reynolds, M. Lochner, G. Ladds, B. Frenguelli, Nat. Commun., <strong>13</strong>, 4150 (2022)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41580-018-0049-3\" target=\"_blank\">[12] D. Wootten, A. Christopoulos, M. Marti-Solano, M. Babu, P. Sexton, Nat. Rev. Mol. Cell. Biol., <strong>19</strong>, 638-653 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41594-017-0011-7\" target=\"_blank\">[13] D. Hilger, M. Masureel, B. Kobilka, Nat. Struct. Mol. Biol., <strong>25</strong>, 4-12 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41467-025-57034-y\" target=\"_blank\">[14] D. Aranda-García, T. Stepniewski, M. Torrens-Fontanals, A. García-Recio, M. Lopez-Balastegui, B. Medel-Lacruz, A. Morales-Pastor, A. Peralta-García, M. Dieguez-Eceolaza, D. Sotillo-Nuñez, T. Ding, M. Drabek, C. Jacquemard, J. Jakowiecki, W. Jespers, M. Jiménez-Rosés, V. Jun-Yu-Lim, A. Nicoli, U. Orzel, A. Shahraki, J. Tiemann, V. Ledesma-Martin, F. Nerín-Fonz, S. Suárez-Dou, O. Canal, G. Pándy-Szekeres, J. Mao, D. Gloriam, E. Kellenberger, D. Latek, R. Guixà-González, H. Gutiérrez-de-Terán, I. Tikhonova, P. Hildebrand, M. Filizola, M. Babu, A. Di Pizio, S. Filipek, P. Kolb, A. Cordomi, T. Giorgino, M. Marti-Solano, J. Selent, Nat. Commun., <strong>16</strong>, 2020 (2025)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41586-018-0259-z\" target=\"_blank\">[15] D. Thal, A. Glukhova, P. Sexton, A. Christopoulos, Nature, <strong>559</strong>, 45-53 (2018)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.tips.2020.12.005\" target=\"_blank\">[16] L. Slosky, M. Caron, L. Barak, Trends in Pharmacological Sciences, <strong>42</strong>, 283-299 (2021)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.apsb.2023.07.020\" target=\"_blank\">[17] C. Zhu, X. Lan, Z. Wei, J. Yu, J. Zhang, Acta Pharmaceutica Sinica B, <strong>14</strong>, 67-86 (2024)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.chempr.2024.08.004\" target=\"_blank\">[18] V. D’Amore, P. Conflitti, L. Marinelli, V. Limongelli, Chem, <strong>10</strong>, 3678-3698 (2024)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41557-023-01238-6\" target=\"_blank\">[19] A. Mafi, S. Kim, W. Goddard, Nat. Chem., <strong>15</strong>, 1127-1137 (2023)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41594-024-01334-2\" target=\"_blank\">[20] H. Batebi, G. Pérez-Hernández, S. Rahman, B. Lan, A. Kamprad, M. Shi, D. Speck, J. Tiemann, R. Guixà-González, F. Reinhardt, P. Stadler, M. Papasergi-Scott, G. Skiniotis, P. Scheerer, B. Kobilka, J. Mathiesen, X. Liu, P. Hildebrand, Nat. Struct. Mol. Biol., <strong>31</strong>, 1692-1701 (2024)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.cell.2015.04.043\" target=\"_blank\">[21] A. Manglik, T. Kim, M. Masureel, C. Altenbach, Z. Yang, D. Hilger, M. Lerch, T. Kobilka, F. Thian, W. Hubbell, R. Prosser, B. Kobilka, Cell, <strong>161</strong>, 1101-1111 (2015)</a><br>\r\n<a href=\"https://doi.org/10.1016/j.cell.2020.03.003\" target=\"_blank\">[22] M. Congreve, C. de Graaf, N. Swain, C. Tate, Cell, <strong>181</strong>, 81-91 (2020)</a><br>\r\n<a href=\"https://doi.org/10.1038/s41573-025-01139-y\" target=\"_blank\">[23] J. Lorente, A. Sokolov, G. Ferguson, H. Schiöth, A. Hauser, D. Gloriam, Nat. Rev. Drug. Discov., <strong>24</strong>, 458-479 (2025)</a><br>\r\n<a href=\"https://doi.org/10.1111/bph.16495\" target=\"_blank\">[24] M. Lopez‐Balastegui, T. Stepniewski, M. Kogut‐Günthel, A. Di Pizio, M. Rosenkilde, J. Mao, J. Selent, British. J. Pharmacology., <strong>182</strong>, 3211-3224 (2024)</a>\r\n</p><div class=\"active tab-pane\"> </div>",
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            "description": "<p>This paper studies optimal financial flexibility in debt issuance. A borrower raises funds for an initial investment and may need financing after observing a private liquidity shock. Under non exclusive lending, new lenders price only their claims, so additional borrowing dilutes existing debt and leads to excessive leverage. The optimal simple debt contract is an endogenous debt limit. It captures the intertemporal commitment–flexibility tradeoff: more borrowing today fi nances investment but increases dilution incentives, requiring tighter limits on future borrowing. Richer clauses, including performance-sensitive debt and contingent prepayment provisions, re store the exclusive-lending benchmark by compensating existing lenders when new financing is raised.</p>",
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            "id": 72194,
            "title": "Neuro-X seminar: Prof Tim O'Shea - Engineering astrocytes to promote wound repair and modulate foreign body responses in the CNS",
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            "event_url": "https://memento.epfl.ch/event/neuro-x-seminar-prof-tim-o-shea-engineering-astroc",
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            "description": "<p>Astrocytes are the predominant glial cells in the mammalian central nervous system (CNS) and play essential roles in maintaining neural circuit activity and tissue homeostasis. In response to CNS insult, including traumatic injury or implantation of a medical device, astrocytes undergo a conserved, temporally regulated reprogramming that reshapes their prioritized functions to protect adjacent neural tissue. The nature and extent of astrocyte reprogramming critically influences outcomes after CNS insult. For example, regeneration after traumatic CNS injury in adult mammals is limited by local responding astrocytes lacking sufficient self-renewal capacity. By contrast, the CNS of neonate (newborn) mammals possesses exceptional parenchymal repair capacity owing to immature astrocytes with elevated proliferative and migratory potential. In the context of an implanted medical device, the spatial extent of astrocyte reprogramming and how impacted astrocytes respond to any further device micromotion, latent infection, or other persistent device-derived stimuli, dictates device performance and longevity. Engineering astrocyte responses to promote targeted functional gains while preserving key capabilities of healthy neural tissue astrocytes will be critical to enabling effective neural regeneration therapies and improving long-term performance of implanted devices. In this talk, I will outline our emerging understanding of how adult astrocytes adaptively reprogram in response to CNS injury and implanted foreign bodies, drawing insights from innovative astrocyte-specific transcriptomic bioassays. I will also provide an overview of biomaterial and cell-grafting strategies that we are exploring to direct astrocyte responses in preclinical models of stroke, spinal cord injury, and foreign body responses.<br>\r\n<br>\r\n<strong>Bio:</strong><br>\r\n<strong>Dr. Timothy O’Shea, PhD</strong> is an Assistant Professor in the Biomedical Engineering department at Boston University (BU). Tim grew up in Brisbane, Australia and completed a Bachelor of Medical Engineering (First Class Honours) and a Masters in Engineering Management at Queensland University of Technology (QUT) before moving to the US for graduate school. He completed his PhD study in Medical Engineering and Medical Physics within the collaborative Health Sciences and Technology program of the Harvard Medical School and the Massachusetts Institute of Technology where we conducted PhD thesis research with Institute Professor Robert Langer. As a Postdoctoral Fellow in Neurobiology at UCLA, he worked with Professors Michael Sofroniew (Neurobiology) and Timothy Deming (Bioengineering) developing and testing novel bioengineering tools to study biological mechanisms involved in CNS injury and repair as well as the CNS foreign body response to implants. Since Fall 2020 he has been leading the Glia Engineering Lab at BU where he has received numerous awards including the Maximizing Investigators' Research Award (MIRA) from NIH and grants from several spinal cord injury research foundations such as Craig H Neilsen, Paralyzed Veterans of America, Bryon Reisch, and Wings for Life.</p>",
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            "organizer": "<a href=\"http://people.epfl.ch/mark.anderson\">Mark Anderson</a>",
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        {
            "id": 72357,
            "title": "Materials for the Future",
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            "start_date": "2026-10-09",
            "end_date": "2026-10-09",
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            "end_time": "19:30:00",
            "description": "<p>In 2026, EPFL named Professor Konstantin Novoselov its first-ever EPFL Fellow, a newly created honorary title recognising scientific personalities of exceptional international stature.<br>\r\n<br>\r\nEPFL is delighted to host a public lecture to celebrate this nomination of one of the most influential physicists of our time.<br>\r\n<br>\r\nKonstantin Novoselov was awarded the Nobel Prize in Physics in 2010 and is globally renowned for his pioneering work on graphene and two-dimensional materials. By isolating graphene for the first time, a sheet of carbon just one atom thick, he opened an entirely new field of research, with profound implications for electronics, energy and quantum technologies.<br>\r\n<br>\r\n<em>Picture this: it was from the graphite of an ordinary pencil lead that this \"super-material\" was first isolated. Using nothing more than a piece of adhesive tape to peel away a layer a single atom thick, Konstantin Novoselov revealed to the world a material with extraordinary properties. A million times thinner than a human hair, 200 times stronger than steel and remarkably conductive, graphene pushes every limit. From the lead of your pencil to the batteries of tomorrow, join us to  discover how a deceptively simple gesture set off a genuine technological revolution.</em><br>\r\n<br>\r\nThis Campus Lecture offers an introduction to that revolution: how a two-dimensional material is transforming our understanding of matter and how today's fundamental discoveries become tomorrow's technologies.<br>\r\n<br>\r\n<strong>About Konstantin Novoselov</strong><br>\r\nKonstantin Novoselov is a physicist specialising in condensed matter and nanotechnology. He conducted his Nobel Prize–winning research at the University of Manchester, where, together with Professor Andre Geim, he isolated graphene for the first time. He has held academic positions in the United Kingdom as well as internationally and is currently based at the National University of Singapore. Widely recognised as a leading figure in the study and application of two-dimensional materials, he has received numerous honours for his contributions to science.</p>",
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            "start_time": "09:00:00",
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            "description": "<div class=\"container-full my-3\">\r\n<div class=\"hero\">\r\n<div class=\"hero-img\"><u><strong>About</strong></u></div>\r\n</div>\r\n</div>\r\nThe Confluence Workshop will explore the future of computing, focusing on the ideas that emerge at the boundaries between traditional areas. The program will feature invited talks, brainstorming sessions, and open discussion. It should be a lot of fun.<br>\r\n<br>\r\n<strong><u>Speakers</u></strong><br>\r\nThe workshop will feature a mix of junior and senior speakers known for creative work that crosses disciplinary boundaries.<br>\r\n<br>\r\n<u><strong>Program</strong></u>\r\n\r\n<ul>\r\n\t<li>Thursday, 8 October : Talks, Panels, &amp; Discussion</li>\r\n\t<li>Friday, 9 October: Talks, Brainstorming, &amp; Social Activities</li>\r\n</ul>\r\n<strong><u>Support</u></strong><br>\r\nSponsored by the School of Computer and Communication Sciences<br>\r\n<br>\r\n<a href=\"https://confluence2026.epfl.ch/\">More information</a><br>\r\n ",
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