ChemBio seminar by Prof. Qiu Wang
Event details
| Date | 09.05.2022 |
| Hour | 15:30 › 16:30 |
| Speaker | https://scholars.duke.edu/person/qiu.wang |
| Location |
Genopode B (Unil)
|
| Category | Conferences - Seminars |
| Event Language | English |
Title: New Amination Methods for the Synthesis of Important Nitrogen-Containing Molecules
Abstract: The research in the Wang group centers on developing new methods that can streamline the synthesis and study of novel nitrogen-containing molecules toward advancing our understanding of human disease and the discovery of new therapy. This talk will present the development for an umpolung strategy for alkene aminofunctionalization that engages electrophilic amination olefin activation and the incorporation of diverse heteroatom and carbon nucleophiles. These methods afford a direct and powerful approach to transform simple and readily available olefins into a diverse range of highly valued 1,2-amino functionality, including amino fluoride, diamines, and amino alcohol derivatives. The talk will also present some innovative application of novel nitrogen-containing molecules as potential leads and chemical probes for molecular imaging.
Speaker's Biography: Professor Qiu Wang obtained her Ph.D. from Emory University in Organic Chemistry under the direction of Professor Albert Padwa (2005) and received postdoctoral trainings with Professor Andrew Myers at Harvard University (2005–2007) and Professor Stuart Schreiber at the Broad Institute of Harvard and MIT (2007–2011). Dr. Wang started her independent career in the Department of Chemistry at Duke University in 2011 and is currently Robert R. and Katherine B. Penn Associate Professor of Chemistry. The research of the Wang group centers on developing new chemistry methods and imaging strategies to advance the synthesis and biological studies of nitrogen-containing small-molecule probes and imaging tools, especially those related to cancer and neurodegenerative disease.
Lab website: https://people.duke.edu/~qw29/wang_group/
Abstract: The research in the Wang group centers on developing new methods that can streamline the synthesis and study of novel nitrogen-containing molecules toward advancing our understanding of human disease and the discovery of new therapy. This talk will present the development for an umpolung strategy for alkene aminofunctionalization that engages electrophilic amination olefin activation and the incorporation of diverse heteroatom and carbon nucleophiles. These methods afford a direct and powerful approach to transform simple and readily available olefins into a diverse range of highly valued 1,2-amino functionality, including amino fluoride, diamines, and amino alcohol derivatives. The talk will also present some innovative application of novel nitrogen-containing molecules as potential leads and chemical probes for molecular imaging.
Speaker's Biography: Professor Qiu Wang obtained her Ph.D. from Emory University in Organic Chemistry under the direction of Professor Albert Padwa (2005) and received postdoctoral trainings with Professor Andrew Myers at Harvard University (2005–2007) and Professor Stuart Schreiber at the Broad Institute of Harvard and MIT (2007–2011). Dr. Wang started her independent career in the Department of Chemistry at Duke University in 2011 and is currently Robert R. and Katherine B. Penn Associate Professor of Chemistry. The research of the Wang group centers on developing new chemistry methods and imaging strategies to advance the synthesis and biological studies of nitrogen-containing small-molecule probes and imaging tools, especially those related to cancer and neurodegenerative disease.
Lab website: https://people.duke.edu/~qw29/wang_group/
Practical information
- Informed public
- Free