Development of Smart DNA Probes for Multiplexed Super-Resolution Microscopy
TWO-DAY LIFE SCIENCE ENGINEERING MINI-SYMPOSIUM
(talk four)
Abstract:
Fluorescence microscopy, an important and widely used tool in biological research, has witnessed a true renaissance since the invention of methods that circumvent the so-called diffraction limit, namely super-resolution techniques. In resonance with these advancements, my work combines advanced high-resolution microscopy with novel approaches from the field of DNA Nanotechnology to push the limits of light microscopy and apply it to cell-biological research. In this presentation, I will describe current advances in DNA-based super-resolution microscopy, including novel immunolabeling strategies, proximity detection, high-throughput imaging, and spectrally unlimited multiplexed imaging.
Bio:
Florian Schueder studied Physics at the Ludwig-Maximilians University of Munich and the Wyss Institute at Harvard University from 2009 to 2015. He then pursued a Ph.D. in Biophysics at the Max Planck Institute of Biochemistry in Martinsried from 2015 to 2020. Since 2021, he has been a Postdoctoral Fellow in the Department of Cell Biology and the Department of Microbial Pathogenesis at Yale School of Medicine.
Zoom link for attending remotely, if needed: https://epfl.zoom.us/j/69315453283
(talk four)
Abstract:
Fluorescence microscopy, an important and widely used tool in biological research, has witnessed a true renaissance since the invention of methods that circumvent the so-called diffraction limit, namely super-resolution techniques. In resonance with these advancements, my work combines advanced high-resolution microscopy with novel approaches from the field of DNA Nanotechnology to push the limits of light microscopy and apply it to cell-biological research. In this presentation, I will describe current advances in DNA-based super-resolution microscopy, including novel immunolabeling strategies, proximity detection, high-throughput imaging, and spectrally unlimited multiplexed imaging.
Bio:
Florian Schueder studied Physics at the Ludwig-Maximilians University of Munich and the Wyss Institute at Harvard University from 2009 to 2015. He then pursued a Ph.D. in Biophysics at the Max Planck Institute of Biochemistry in Martinsried from 2015 to 2020. Since 2021, he has been a Postdoctoral Fellow in the Department of Cell Biology and the Department of Microbial Pathogenesis at Yale School of Medicine.
Zoom link for attending remotely, if needed: https://epfl.zoom.us/j/69315453283
Practical information
- Informed public
- Free
Organizer
- Prof. Felix Naef, & Prof. Matteo Dal Peraro, School of Life Sciences, EPFL
Contact
- Institute of Bioengineering (IBI), Dietrich REINHARD