Directional stimulation improves DBS therapy: from Computer model prediction to human use

Thumbnail

Event details

Date 21.03.2016
Hour 14:0015:00
Speaker Prof. Claudio Pollo, Bern University Hospital
Bio: Claudio Pollo is responsible for stereotactic and functional neurosurgery for epilepsy surgery and radiosurgery program at the Department of Neurosurgery. During his training, he focused his clinical and scientific interests on functional neurosurgery and epilepsy surgery (Prof. Jean-Guy Villemure). His professional training and specialization in functional neurosurgery was deepened by working as a researcher at the University Hospital Joseph Fourier, Grenoble (Prof. Alim-Louis Benabid). He wrote his doctoral thesis on deep brain stimulation in the subthalamic nucleus in Parkinson disease.

In 2004 he received a postgraduate diploma in biomedical engineering at the Federal Institute of Technology (EPFL). In 2006 he was awarded the academic degree PD & MER of the Medical Faculty of the University of Lausanne (UNIL). Most of his publications and research projects, supported by the Swiss National Science Foundation (SNSF) or the Commission for Technology and Innovation (CTI) of the Federal, deal with epilepsy surgery, deep brain stimulation for movement disorders and epilepsy, with functionality and technological aspects of electrical stimulation and with image processing processes.
Location
Category Conferences - Seminars
Deep brain stimulation of different targets has been shown to drastically improve symptoms of a variety of neurological conditions. However, the occurrence of disabling side effects may limit the ability to deliver adequate amounts of current necessary to reach the maximal benefit. Computed models have suggested that reduction in electrode size and the ability to provide directional stimulation could increase the efficacy of such therapies, especially in targets used for the therapy of movement disorders like Parkinson’s disease or essential tremor. Intraoperative studies performed in human have shown that directional stimulation provides different thresholds for clinical effects increasing the therapeutic window and needing a low therapeutic current.

Recently we were able to investigate the effect of directional stimulation on beneficial and side effects, in chronically implanted patients compared to omnidirectional stimulation and report our preliminary experience with this new device and how could this device used in the future.

Practical information

  • Informed public
  • Free

Organizer

  • Center for Neuroprosthetics, Professor Dimitri Van De Ville

Tags

deep brain stimulation directional electrode Parkinson’s disease Essential tremor volume of tissue activated

Event broadcasted in

Share