Does Quantum Gravity constrain Large-Field Inflation?

I will start by recalling the theoretical interest in large-field inflation and its relation to potential future observations, e.g. through primordial gravitational waves. I will then outline the possible fundamental obstructions to realizing such inflationary scenarios, both in string theory and in quantum gravity in general. The focus will in particular be on the recent scientific debate in the context of the Weak Gravity Conjecture, Gravitational Instantons and the Swampland Paradigm.