Elucidating the Rules of Life through in vivo Chemical Microscopy
Event details
| Date | 08.10.2018 |
| Hour | 12:15 › 13:15 |
| Speaker | Prof. Ji-Xin Cheng, Photonics Center, Boston University, Boston, MA (USA) |
| Location | |
| Category | Conferences - Seminars |
DISTINGUISHED LECTURE IN BIOLOGICAL ENGINEERING
(sandwiches served)
Abstract:
Until now, understanding of the exceptionally fast and selective chemistry occurring inside single living cells has been very limited, partly because conventional chemical assays essentially treat the cell, a highly dynamic structure, as a static bag of molecules. My research is devoted to addressing this challenge by developing in vivo spectroscopy methods enabling direct visualization of chemical distribution and dynamics in a living system. We have been pushing the physical limits of in vivo chemical microscopy in terms of sensitivity, speed and spatial resolution through continuous innovations in instrumentation and data science. We further apply this tools to reveal hidden signatures in cancer metabolism, neuroscience and infectious disease. The unveiled signatures open new opportunities for early diagnosis and/or precision treatment. We are also committed to converting our technologies into scientific instruments for broader use by non-experts and medical devices for clinical use.
Bio:
Ji-Xin Cheng was born in Jixi, Anhui Province, P. R. China in 1971. He attended University of Science and Technology of China (USTC) from 1989 to 1994. From 1994 to 1998, he carried out his Ph.D. study on bond-selective chemistry under the supervision of Qingshi Zhu at USTC. As a graduate student, he worked as a research assistant at Universite Paris-sud (France) on vibrational spectroscopy and the Hong Kong University of Science and Technology (HKUST) on quantum dynamics theory. After postdoctoral training on ultrafast spectroscopy in Yijing Yan’s group at HKUST, he joined Sunney Xie’s group at Harvard University as a postdoc, where he and others developed CARS microscopy that allows high-speed vibrational imaging of cells and tissues. Cheng joined Purdue University in 2003 as Assistant Professor in Weldon School of Biomedical Engineering and Department of Chemistry, promoted to Associate Professor in 2009 and Full Professor in 2013. He joined Boston University as the Moustakas Professor in Photonics and Optoelectronics in summer 2017.
(sandwiches served)
Abstract:
Until now, understanding of the exceptionally fast and selective chemistry occurring inside single living cells has been very limited, partly because conventional chemical assays essentially treat the cell, a highly dynamic structure, as a static bag of molecules. My research is devoted to addressing this challenge by developing in vivo spectroscopy methods enabling direct visualization of chemical distribution and dynamics in a living system. We have been pushing the physical limits of in vivo chemical microscopy in terms of sensitivity, speed and spatial resolution through continuous innovations in instrumentation and data science. We further apply this tools to reveal hidden signatures in cancer metabolism, neuroscience and infectious disease. The unveiled signatures open new opportunities for early diagnosis and/or precision treatment. We are also committed to converting our technologies into scientific instruments for broader use by non-experts and medical devices for clinical use.
Bio:
Ji-Xin Cheng was born in Jixi, Anhui Province, P. R. China in 1971. He attended University of Science and Technology of China (USTC) from 1989 to 1994. From 1994 to 1998, he carried out his Ph.D. study on bond-selective chemistry under the supervision of Qingshi Zhu at USTC. As a graduate student, he worked as a research assistant at Universite Paris-sud (France) on vibrational spectroscopy and the Hong Kong University of Science and Technology (HKUST) on quantum dynamics theory. After postdoctoral training on ultrafast spectroscopy in Yijing Yan’s group at HKUST, he joined Sunney Xie’s group at Harvard University as a postdoc, where he and others developed CARS microscopy that allows high-speed vibrational imaging of cells and tissues. Cheng joined Purdue University in 2003 as Assistant Professor in Weldon School of Biomedical Engineering and Department of Chemistry, promoted to Associate Professor in 2009 and Full Professor in 2013. He joined Boston University as the Moustakas Professor in Photonics and Optoelectronics in summer 2017.
Practical information
- Informed public
- Free
Organizer
Contact
- Institute of Bioengineering (IBI, Christina Mattsson)