EPFL BioE Talks SERIES "From the Development of Highly Adhesive Hydrogels to the Prevention of Concussion in Sport Contact: Dissipation as a Central Thema"
Event details
| Date | 16.11.2020 |
| Hour | 16:30 › 17:00 |
| Speaker | Prof. Dominique Pioletti, Institute of Bioengineering and Institute of Mechanical Engineering, EPFL, Lausanne (CH) |
| Location | Online |
| Category | Conferences - Seminars |
WEEKLY EPFL BIOE TALKS SERIES
(note that this talk is number two of a double-feature seminar - see details of the first talk here)
Abstract:
To quote Prof. Clifford Truesdell, “dissipation is the rule rather than the exception”. The study of this phenomenon is therefore of prime importance if we want to obtain a precise description of the mechanical behavior and the biological functions of soft tissues. As example, we previously showed that the dissipation arising in knee cartilage during physical activities was responsible for a local temperature increase in this tissue favoring chondrogenesis. Dissipation is however a general term that does not discriminate between the different dissipation sources at play in soft tissues submitted to dynamic loading. The dissipation sources can be of reversible or irreversible nature which have fundamental different physical properties. In this talk, I will present the way we consider and control the dissipative phenomena in the development of materials such as hydrogels to increase their mechanical properties. In particular, I will highlight the central aspect of dissipation in developing highly adhesive hydrogels or soft materials that could be used in the prevention of concussion in sport contact.
Bio:
Dominique Pioletti obtained a Master’s degree in Physics at EPFL in 1992. He pursued his education in the same Institution and obtained his PhD in biomechanics in 1997. He developed original constitutive laws for soft tissues taking into account viscoelasticity in large deformation situations. Then he spent two years at UCSD as a post-doc fellow and was interested in particular in understanding the molecular and cellular mechanisms leading to peri-implant osteolysis. At that time the pioneered idea to use the orthopedic implant as drug delivery system and has since proposed different solutions relevant for clinical applications. In particular, he co-founded a start-up (flowbone.com) to translate into a clinical application the development of an injectable hydrogel used to prevent osteoporotic fracture. From 2006 to 2013, he was an Assistant Professor at EPFL and since August 2013, was appointed Associate Professor (with tenure) of Biomechanics at EPFL. He is the director of the Laboratory of Biomechanical Orthopedics. His research topics include biomechanics of the musculoskeletal system, mechanobiology in bone and cartilage, drug delivery system for bone and cartilage, functional tissue engineering. His close collaboration with different hospital departments has resulted in research output oriented toward applications.
Zoom link (with registration) for attending remotely: https://go.epfl.ch/EPFLBioETalks
IMPORTANT NOTICE: due to restrictions resulting from the ongoing Covid-19 situation, this seminar can be followed via Zoom web-streaming only, following prior one-time registration through the link above.
(note that this talk is number two of a double-feature seminar - see details of the first talk here)
Abstract:
To quote Prof. Clifford Truesdell, “dissipation is the rule rather than the exception”. The study of this phenomenon is therefore of prime importance if we want to obtain a precise description of the mechanical behavior and the biological functions of soft tissues. As example, we previously showed that the dissipation arising in knee cartilage during physical activities was responsible for a local temperature increase in this tissue favoring chondrogenesis. Dissipation is however a general term that does not discriminate between the different dissipation sources at play in soft tissues submitted to dynamic loading. The dissipation sources can be of reversible or irreversible nature which have fundamental different physical properties. In this talk, I will present the way we consider and control the dissipative phenomena in the development of materials such as hydrogels to increase their mechanical properties. In particular, I will highlight the central aspect of dissipation in developing highly adhesive hydrogels or soft materials that could be used in the prevention of concussion in sport contact.
Bio:
Dominique Pioletti obtained a Master’s degree in Physics at EPFL in 1992. He pursued his education in the same Institution and obtained his PhD in biomechanics in 1997. He developed original constitutive laws for soft tissues taking into account viscoelasticity in large deformation situations. Then he spent two years at UCSD as a post-doc fellow and was interested in particular in understanding the molecular and cellular mechanisms leading to peri-implant osteolysis. At that time the pioneered idea to use the orthopedic implant as drug delivery system and has since proposed different solutions relevant for clinical applications. In particular, he co-founded a start-up (flowbone.com) to translate into a clinical application the development of an injectable hydrogel used to prevent osteoporotic fracture. From 2006 to 2013, he was an Assistant Professor at EPFL and since August 2013, was appointed Associate Professor (with tenure) of Biomechanics at EPFL. He is the director of the Laboratory of Biomechanical Orthopedics. His research topics include biomechanics of the musculoskeletal system, mechanobiology in bone and cartilage, drug delivery system for bone and cartilage, functional tissue engineering. His close collaboration with different hospital departments has resulted in research output oriented toward applications.
Zoom link (with registration) for attending remotely: https://go.epfl.ch/EPFLBioETalks
IMPORTANT NOTICE: due to restrictions resulting from the ongoing Covid-19 situation, this seminar can be followed via Zoom web-streaming only, following prior one-time registration through the link above.
Practical information
- Informed public
- Registration required
Organizer
Contact
- Institute of Bioengineering (IBI), Dietrich REINHARD