EPFL BioE Talks SERIES "Molecular Electronics With DNA Towards Detection of Nucleic Acids"
Event details
| Date | 14.11.2022 |
| Hour | 16:00 › 17:00 |
| Speaker | Prof. Danny Porath, Institute of Chemistry and Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem (IL) |
| Location | Online |
| Category | Conferences - Seminars |
| Event Language | English |
WEEKLY EPFL BIOE TALKS SERIES
Abstract:
The DNA double-strand recognition, as well as the ability to manipulate its structure open a multitude of ways to make DNA useful for molecular electronics. We recently reported a breakthrough in measuring charge transport in DNA (Nature Nanotechnology 2020) in a special configuration. This finding is of great importance by itself for understanding electricity in DNA in particular, and for molecular electronics in general. However, it also paves the way for the design of new ultra-sensitive detectors for DNA and RNA. Addressing these challenges is at the heart of the current pandemic as well as for early detection of cancer.
References:
[1] "Direct measurement of electrical transport through DNA molecules", Danny Porath, Alexey Bezryadin, Simon de Vries and Cees Dekker, Nature 403, 635 (2000).
[2] "Charge Transport in DNA-based Devices", Danny Porath, Rosa Di Felice and Gianaurelio Cuniberti, Topics in Current Chemistry Vol. 237, pp. 183-228 Ed. Gary Shuster. Springer Verlag, 2004.
[3] "Long-range charge transport in single G4-DNA molecules", Gideon I. Livshits et. al., Nature Nanotechnology 9, 1040 (2014).
[4] “Advances in Synthesis and Measurement of Charge Transport in DNA-Based Derivatives”. R. Zhuravel, A. Stern, N. Fardian‐Melamed, G. Eidelshtein, L. Katrivas, D. Rotem, A. Kotlyar and D. Porath, Advanced Materials 30, 1706984 (2018).
[5] "Backbone charge transport in double-stranded DNA", R. Zhuravel et. al., Nature Nanotechnology, 15(10), 836 (2020)..
Bio:
Education:
1997-2000 Postdoctoral work, Delft University of Technology, The Netherlands
1993-1997 Ph.D., Physics, The Hebrew University of Jerusalem
1990-1993 M.Sc., Physics, The Hebrew University of Jerusalem
1985-1988 B.Sc., Physics, Mathematics, Electronics, Hebrew University of Jerusalem
Professional experiences (in reverse chronological order):
2017- Vice Dean Research, Faculty of Science, Hebrew University of Jerusalem
2016- Full Professor, Institute of Chemistry, The Hebrew University of Jerusalem
2013- Etta and Paul Schankerman Chair of Molecular BioMedicine
2011-2014 Director of the HUJI Center for Nanoscience and Nanotechnology
2009-2016 Associate Professor, Institute of Chemistry, Hebrew University of Jerusalem
2007-2009 Senior Lecturer, Institute of Chemistry, Hebrew University of Jerusalem
2001-2007 Lecturer, Institute of Chemistry, Hebrew University of Jerusalem.
Zoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks
Instructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:
IF you are not attending in-person in the room, please make sure to
Abstract:
The DNA double-strand recognition, as well as the ability to manipulate its structure open a multitude of ways to make DNA useful for molecular electronics. We recently reported a breakthrough in measuring charge transport in DNA (Nature Nanotechnology 2020) in a special configuration. This finding is of great importance by itself for understanding electricity in DNA in particular, and for molecular electronics in general. However, it also paves the way for the design of new ultra-sensitive detectors for DNA and RNA. Addressing these challenges is at the heart of the current pandemic as well as for early detection of cancer.
References:
[1] "Direct measurement of electrical transport through DNA molecules", Danny Porath, Alexey Bezryadin, Simon de Vries and Cees Dekker, Nature 403, 635 (2000).
[2] "Charge Transport in DNA-based Devices", Danny Porath, Rosa Di Felice and Gianaurelio Cuniberti, Topics in Current Chemistry Vol. 237, pp. 183-228 Ed. Gary Shuster. Springer Verlag, 2004.
[3] "Long-range charge transport in single G4-DNA molecules", Gideon I. Livshits et. al., Nature Nanotechnology 9, 1040 (2014).
[4] “Advances in Synthesis and Measurement of Charge Transport in DNA-Based Derivatives”. R. Zhuravel, A. Stern, N. Fardian‐Melamed, G. Eidelshtein, L. Katrivas, D. Rotem, A. Kotlyar and D. Porath, Advanced Materials 30, 1706984 (2018).
[5] "Backbone charge transport in double-stranded DNA", R. Zhuravel et. al., Nature Nanotechnology, 15(10), 836 (2020)..
Bio:
Education:
1997-2000 Postdoctoral work, Delft University of Technology, The Netherlands
1993-1997 Ph.D., Physics, The Hebrew University of Jerusalem
1990-1993 M.Sc., Physics, The Hebrew University of Jerusalem
1985-1988 B.Sc., Physics, Mathematics, Electronics, Hebrew University of Jerusalem
Professional experiences (in reverse chronological order):
2017- Vice Dean Research, Faculty of Science, Hebrew University of Jerusalem
2016- Full Professor, Institute of Chemistry, The Hebrew University of Jerusalem
2013- Etta and Paul Schankerman Chair of Molecular BioMedicine
2011-2014 Director of the HUJI Center for Nanoscience and Nanotechnology
2009-2016 Associate Professor, Institute of Chemistry, Hebrew University of Jerusalem
2007-2009 Senior Lecturer, Institute of Chemistry, Hebrew University of Jerusalem
2001-2007 Lecturer, Institute of Chemistry, Hebrew University of Jerusalem.
Zoom link (with one-time registration for the whole series) for attending remotely: https://go.epfl.ch/EPFLBioETalks
Instructions for 1st-year Ph.D. students who are under EDBB’s mandatory seminar attendance rule:
IF you are not attending in-person in the room, please make sure to
- send D. Reinhard a note before noon on seminar day, informing that you plan to attend the talk online, and
- be signed in on Zoom with a recognizable user name (not a pseudonym making it difficult or impossible to be identified).
Practical information
- Informed public
- Registration required
Organizer
Contact
- Institute of Bioengineering (IBI), Dietrich REINHARD